Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GNAI3 | P08754 | 2/20 | 0.72 |
| ▸ | GNAO1 | P09471 | 2/20 | 0.72 |
| ▸ | GNAI1 | P63096 | 2/20 | 0.72 |
| ▸ | SAT1 | P21673 | 1/20 | 0.63 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.52 |
| ▸ | TSHR | P16473 | 1/20 | 0.52 |
| ▸ | S1PR2 | O95136 | 5/20 | 0.44 |
| ▸ | S1PR4 | O95977 | 5/20 | 0.44 |
| ▸ | S1PR1 | P21453 | 5/20 | 0.44 |
| ▸ | S1PR3 | Q99500 | 5/20 | 0.44 |
| ▸ | S1PR5 | Q9H228 | 1/20 | 0.44 |
| ▸ | EPHX1 | P07099 | 3/20 | 0.43 |
| ▸ | NAAA | Q02083 | 1/20 | 0.43 |
| ▸ | ADH1B | P00325 | 1/20 | 0.43 |
| ▸ | ADH1C | P00326 | 1/20 | 0.43 |
| ▸ | ADH1A | P07327 | 1/20 | 0.43 |
| ▸ | ADH4 | P08319 | 1/20 | 0.43 |
| ▸ | ADH7 | P40394 | 1/20 | 0.43 |
| ▸ | GBA1 | P04062 | 3/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7767956 | 1.00 | GNAI3 (0.72) | GNAI3GNAO1GNAI1SAT1ALDH1A1 | |
| SCHEMBL1933069 | 1.00 | GNAI3 (0.72) | GNAI3GNAO1GNAI1SAT1ALDH1A1 | |
| SCHEMBL11539085 | 1.00 | GNAI3 (0.72) | GNAI3GNAO1GNAI1SAT1ALDH1A1 | |
| SCHEMBL19414059 | 1.00 | GNAI3 (0.72) | GNAI3GNAO1GNAI1SAT1ALDH1A1 | |
| SCHEMBL17718455 | 1.00 | GNAI3 (0.72) | GNAI3GNAO1GNAI1SAT1ALDH1A1 | |
| SCHEMBL11541786 | 1.00 | GNAI3 (0.72) | GNAI3GNAO1GNAI1SAT1ALDH1A1 | |
| SCHEMBL23468518 | 0.98 | GNAI3 (0.70) | GNAI3GNAO1GNAI1SAT1ALDH1A1 | |
| SCHEMBL23468533 | 0.98 | GNAI3 (0.70) | GNAI3GNAO1GNAI1SAT1ALDH1A1 | |
| SCHEMBL1678880 | 0.98 | GNAI3 (0.69) | GNAI3GNAO1GNAI1SAT1ALDH1A1 | |
| SCHEMBL7766302 | 0.98 | GNAI3 (0.69) | GNAI3GNAO1GNAI1SAT1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9644000-B2 | V1a receptor agonists | FERRING B.V. (NL) | 2017-05-09 | — | — | US | disclosed |
| US-9388214-B2 | V1A receptor agonists | FERRING B.V. (NL) | 2016-07-12 | — | — | US | disclosed |
| US-20150126432-A1 | V1a Receptor Agonists | OCELOT BIO, INC. | 2015-05-07 | — | — | US | disclosed |
| US-7923573-B2 | Benzene compound having 2 or more substituents | DAIICHI SANKYO COMPANY, LIMITED (JP) | 2011-04-12 | — | — | US | disclosed |
| US-20080255111-A1 | Tissue Factor Production Inhibitor | SANKYO COMPANY LIMITED (JP) | 2008-10-16 | — | — | US | disclosed |
| US-20080004301-A1 | Benzene Compound Having 2 or More Substituents | DAIICHI SANKYO COMPANY, LIMITED (JP) | 2008-01-03 | — | — | US | disclosed |
| EP-1806332-A1 | BENZENE COMPOUND HAVING 2 OR MORE SUBSTITUENTS | Daiichi Sankyo Company, Limited (JP) | 2007-07-11 | — | — | EP | disclosed |
| EP-1764075-A1 | TISSUE FACTOR PRODUCTION INHIBITOR | Sankyo Company, Limited (JP) | 2007-03-21 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150126432-A1 | V1a Receptor Agonists | AVPR2, AVPR1A, AVPR1B | GNAI3 759/4885GNAO1 527/4885GNAI1 520/4885 |
| US-20080255111-A1 | Tissue Factor Production Inhibitor | PTAFR, PLAT, TFPI | GNAI3 1878/4885GNAO1 2401/4885GNAI1 1799/4885 |
| US-20080004301-A1 | Benzene Compound Having 2 or More Substituents | NR1H2, NR1H3, NCOR2 | GNAI3 2801/4885GNAO1 735/4885GNAI1 2632/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.