Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADH1A | P07327 | 8/20 | 0.48 |
| ▸ | ADH1C | P00326 | 5/20 | 0.48 |
| ▸ | PHGDH | O43175 | 2/20 | 0.42 |
| ▸ | FAAH | O00519 | 1/20 | 0.42 |
| ▸ | MGLL | Q99685 | 1/20 | 0.42 |
| ▸ | ADH4 | P08319 | 1/20 | 0.39 |
| ▸ | ADH1B | P00325 | 1/20 | 0.37 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.37 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | MEN1 | O00255 | 2/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1356265 | 1.00 | ADH1A (0.48) | ADH1AADH1CPHGDHFAAHMGLL | |
| SCHEMBL1679036 | 1.00 | ADH1A (0.48) | ADH1AADH1CPHGDHFAAHMGLL | |
| Hydrochloric Acid SCHEMBL1354676 | 0.97 | ADH1A (0.46) | ADH1AADH1CPHGDHFAAHMGLL | |
| SCHEMBL20725618 | 0.97 | ADH1A (0.50) | ADH1AADH1CPHGDHFAAHMGLL | |
| SCHEMBL23072500 | 0.97 | ADH1A (0.50) | ADH1AADH1CPHGDHFAAHMGLL | |
| SCHEMBL23072499 | 0.97 | ADH1A (0.50) | ADH1AADH1CPHGDHFAAHMGLL | |
| SCHEMBL24914755 | 0.97 | ADH1A (0.50) | ADH1AADH1CPHGDHFAAHMGLL | |
| SCHEMBL20733077 | 0.97 | ADH1A (0.50) | ADH1AADH1CPHGDHFAAHMGLL | |
| SCHEMBL22212587 | 0.97 | ADH1A (0.50) | ADH1AADH1CPHGDHFAAHMGLL | |
| SCHEMBL20887811 | 0.97 | ADH1A (0.50) | ADH1AADH1CPHGDHFAAHMGLL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7923573-B2 | Benzene compound having 2 or more substituents | DAIICHI SANKYO COMPANY, LIMITED (JP) | 2011-04-12 | — | — | US | disclosed |
| US-20080255111-A1 | Tissue Factor Production Inhibitor | SANKYO COMPANY LIMITED (JP) | 2008-10-16 | — | — | US | disclosed |
| US-20080004301-A1 | Benzene Compound Having 2 or More Substituents | DAIICHI SANKYO COMPANY, LIMITED (JP) | 2008-01-03 | — | — | US | disclosed |
| EP-1806332-A1 | BENZENE COMPOUND HAVING 2 OR MORE SUBSTITUENTS | Daiichi Sankyo Company, Limited (JP) | 2007-07-11 | — | — | EP | disclosed |
| EP-1764075-A1 | TISSUE FACTOR PRODUCTION INHIBITOR | Sankyo Company, Limited (JP) | 2007-03-21 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080255111-A1 | Tissue Factor Production Inhibitor | PTAFR, PLAT, TFPI | ADH1A 4118/4885ADH1C 4567/4885PHGDH 2573/4885 |
| US-20080004301-A1 | Benzene Compound Having 2 or More Substituents | NR1H2, NR1H3, NCOR2 | ADH1A 2316/4885ADH1C 3082/4885PHGDH 4494/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.