Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR1H2 | P55055 | 11/20 | 0.62 |
| ▸ | RXRA | P19793 | 9/20 | 0.62 |
| ▸ | NR1H3 | Q13133 | 9/20 | 0.62 |
| ▸ | AAK1 | Q2M2I8 | 2/20 | 0.46 |
| ▸ | HIF1A | Q16665 | 3/20 | 0.43 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.39 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1679021 | 0.83 | AAK1 (0.45) | NR1H2RXRANR1H3AAK1HIF1A | |
| SCHEMBL1679367 | 0.81 | NR1H2 (0.72) | NR1H2RXRANR1H3FFAR1SRD5A2 | |
| SCHEMBL1678959 | 0.80 | NR1H2 (0.62) | NR1H2RXRANR1H3AAK1HIF1A | |
| SCHEMBL1678558 | 0.76 | RXRA (1.00) | NR1H2RXRANR1H3FFAR1 | |
| SCHEMBL1679004 | 0.74 | NR1H2 (0.82) | NR1H2RXRANR1H3 | |
| SCHEMBL17129337 | 0.74 | MAOB (0.55) | FFAR1 | |
| SCHEMBL1679384 | 0.74 | NR1H2 (0.73) | NR1H2RXRANR1H3FFAR1 | |
| SCHEMBL1679132 | 0.72 | NR1H2 (1.00) | NR1H2RXRANR1H3FFAR1 | |
| SCHEMBL17129613 | 0.72 | MAOB (0.59) | FFAR1 | |
| SCHEMBL13606514 | 0.71 | AAK1 (0.57) | AAK1HIF1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7923573-B2 | Benzene compound having 2 or more substituents | DAIICHI SANKYO COMPANY, LIMITED (JP) | 2011-04-12 | — | — | US | disclosed |
| US-20080004301-A1 | Benzene Compound Having 2 or More Substituents | DAIICHI SANKYO COMPANY, LIMITED (JP) | 2008-01-03 | — | — | US | disclosed |
| EP-1806332-A1 | BENZENE COMPOUND HAVING 2 OR MORE SUBSTITUENTS | Daiichi Sankyo Company, Limited (JP) | 2007-07-11 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080004301-A1 | Benzene Compound Having 2 or More Substituents | NR1H2, NR1H3, NCOR2 | NR1H2 1/4885RXRA 5/4885NR1H3 2/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.