⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12036975 | 0.96 | ADH1A (0.46) | — | |
| Ammonia Solution, Strong SCHEMBL29080997 | 0.96 | — | — | |
| SCHEMBL284507 | 0.96 | — | — | |
| Hydrochloric Acid SCHEMBL313812 | 0.93 | — | — | |
| Ammonia Solution, Strong SCHEMBL2886635 | 0.93 | — | — | |
| SCHEMBL1674941 | 0.93 | ADH1A (0.50) | — | |
| SCHEMBL13356252 | 0.93 | ADH1A (0.50) | — | |
| SCHEMBL283931 | 0.93 | ADH1A (0.50) | — | |
| SCHEMBL20733112 | 0.93 | ADH1A (0.50) | — | |
| SCHEMBL1679002 | 0.93 | ADH1A (0.50) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 212 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115043844-B | TRK kinase inhibitor compounds and uses thereof | 河南迈英诺医药科技有限公司 | 2024-05-17 | — | — | CN | claimed |
| CN-111819176-B | 4-azaindole compounds | 百时美施贵宝公司 | 2023-12-15 | — | — | CN | claimed |
| CN-111491930-B | Substituted Indole Compounds Useful as TLR Inhibitors | 百时美施贵宝公司 | 2023-09-26 | — | — | CN | claimed |
| CN-115043844-A | TRK kinase inhibitor compounds and uses thereof | 河南迈英诺医药科技有限公司 | 2022-09-13 | — | — | CN | claimed |
| CN-112912373-B | Angiogenesis inhibitor, preparation method and application thereof | 北京康辰药业股份有限公司 | 2022-08-23 | — | — | CN | claimed |
| CN-114835570-A | Synthesis method of trans-1, 2-diaminomethyl-cyclobutane and salt thereof | 上海寻科生物医药科技有限公司 | 2022-08-02 | — | — | CN | claimed |
| CN-113416150-B | Synthetic method of lobaplatin intermediate | 上海寻科生物医药科技有限公司 | 2022-05-31 | — | — | CN | claimed |
| CN-113416150-A | Novel synthesis method of lobaplatin intermediate | 上海寻科生物医药科技有限公司 | 2021-09-21 | — | — | CN | claimed |
| CN-112912373-A | Angiogenesis inhibitor, preparation method and application thereof | 北京康辰药业股份有限公司 | 2021-06-04 | — | — | CN | claimed |
| CN-112358469-A | Angiogenesis inhibitor, preparation method and application thereof | 北京康辰药业股份有限公司 | 2021-02-12 | — | — | CN | claimed |
| CN-111819176-A | 4-azaindole compounds | 百时美施贵宝公司 | 2020-10-23 | — | — | CN | claimed |
| CN-111491930-A | Substituted indole compounds useful as T L R inhibitors | 百时美施贵宝公司 | 2020-08-04 | — | — | CN | claimed |
| CN-108624884-B | The PCB surface treating agent and surface treatment method for removing brownification layer and the outstanding copper of blind hole | 昆山市板明电子科技有限公司 | 2019-08-27 | — | — | CN | claimed |
| CN-108624884-A | The PCB surface conditioning agents and surface treatment method for removing brown layer and the outstanding copper of blind hole | 昆山市板明电子科技有限公司 | 2018-10-09 | — | — | CN | claimed |
| CN-108047277-A | The preparation method of liposoluble platinum complex with antitumor activity | 昆明贵研药业有限公司 | 2018-05-18 | — | — | CN | claimed |
| CN-103663484-B | Method for quickly synthesizing SAPO(silicoaluminophosphate)-34 molecular sieve and catalyst prepared from molecular sieve | DALIAN CHEMICAL PHYSICS INST | 2015-06-17 | — | — | CN | claimed |
| CN-103663484-A | Method for quickly synthesizing SAPO(silicoaluminophosphate)-34 molecular sieve and catalyst prepared from molecular sieve | DALIAN CHEMICAL PHYSICS INST | 2014-03-26 | — | — | CN | claimed |
| EP-4739692-A1 | SUBSTITUTED HEXAHYDRO-2H-PYRAZINO[1,2-A]PYRAZIN-1(6H)-ONE DERIVATIVES AS ACTIVATORS OF HUMAN CASEINOLYTIC PROTEASE P (HSCLPP) | Centro Atlantico del Medicamento S.A (Ceamed, S.A) (ES) | 2026-05-13 | — | — | EP | disclosed |
| WO-1980000537-A1 | PYRIMIDO(1,6-A)INDOLE DERIVATIVES | AMERICAN HOME PROD (US) | 1980-04-03 | — | — | WO | disclosed |
| EP-0008950-A2 | Pyrimido(1,6-a)indole derivatives and intermediates therefor, processes for their preparation, pharmaceutical compositions containing the derivatives and their use | AMERICAN HOME PRODUCTS CORPORATION (US) | 1980-03-19 | — | — | EP | disclosed |