Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPA1 | O75762 | 5/20 | 0.47 |
| ▸ | TNNI3K | Q59H18 | 2/20 | 0.44 |
| ▸ | TTBK1 | Q5TCY1 | 2/20 | 0.44 |
| ▸ | TTBK2 | Q6IQ55 | 2/20 | 0.44 |
| ▸ | HPGD | P15428 | 3/20 | 0.43 |
| ▸ | TSHR | P16473 | 3/20 | 0.43 |
| ▸ | TP53 | P04637 | 2/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | KDR | P35968 | 3/20 | 0.40 |
| ▸ | BRAF | P15056 | 1/20 | 0.40 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 2/20 | 0.39 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16788826 | 0.87 | TNNI3K (0.54) | TRPA1TNNI3KTTBK1TTBK2POLB | |
| SCHEMBL14949199 | 0.81 | TTBK1 (0.49) | TRPA1TNNI3KTTBK1TTBK2TSHR | |
| SCHEMBL14949361 | 0.73 | TTBK1 (0.48) | TRPA1TNNI3KTTBK1TTBK2HPGD | |
| SCHEMBL14949390 | 0.72 | TTBK1 (0.50) | TRPA1TNNI3KTTBK1TTBK2TP53 | |
| SCHEMBL12336389 | 0.70 | KDR (0.61) | TRPA1TNNI3KTTBK1TTBK2KDR | |
| SCHEMBL15257736 | 0.66 | CDK2 (0.46) | HPGDTSHRTP53SMN1; SMN2LMNA | |
| SCHEMBL30564544 | 0.65 | TRPA1 (0.75) | TRPA1TNNI3KTTBK1TTBK2KDR | |
| SCHEMBL2882091 | 0.65 | TRPA1 (0.75) | TRPA1TNNI3KTTBK1TTBK2KDR | |
| SCHEMBL14949314 | 0.64 | TTBK1 (0.49) | TRPA1TNNI3KTTBK1TTBK2KDR | |
| SCHEMBL2356649 | 0.62 | CCNK (0.55) | HPGDTSHRLMNAKDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9212151-B2 | Heterocyclic compounds useful for kinase inhibition | AMITECH THERAPEUTIC SOLUTIONS, INC. (US) | 2015-12-15 | — | — | US | disclosed |
| US-20150158828-A1 | Heterocyclic Compounds Useful for Kinase Inhibition | AMITECH THERAPEUTIC SOLUTIONS, INC. | 2015-06-11 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150158828-A1 | Heterocyclic Compounds Useful for Kinase Inhibition | MAP4K2, MAP3K20, MAP3K19 | TRPA1 3600/4885TNNI3K 56/4885TTBK1 221/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.