SCHEMBL16789232

SCHEMBL16789232

Cc1ccccc1N1C(=C2N(c3ccccc3C)C3CCCCC3N2c2ccccc2C)N(c2ccccc2C)C2CCCCC21

nearest known ligand 0.49

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
SLC18A3 Q16572 1/20 0.49
TSHR P16473 1/20 0.43
ALDH1A1 P00352 4/20 0.42
SMN1; SMN2 Q16637 2/20 0.42
HPGD P15428 1/20 0.42
MEN1 O00255 2/20 0.40
KMT2A Q03164 2/20 0.40
ADRB1 P08588 1/20 0.40
KDM4E B2RXH2 1/20 0.40
LMNA P02545 1/20 0.40
NPSR1 Q6W5P4 1/20 0.40
L3MBTL1 Q9Y468 1/20 0.40
ATM Q13315 1/20 0.40
MAPT P10636 2/20 0.39
MGLL Q99685 1/20 0.38
ALOX5 P09917 2/20 0.38
HTT P42858 1/20 0.36
DDB1 Q16531 1/20 0.35
CRBN Q96SW2 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16789238 0.91 SLC18A3 (0.43) SLC18A3TSHRALDH1A1SMN1; SMN2HPGD
SCHEMBL20071756 0.84 KMT2A (0.40) SLC18A3TSHRSMN1; SMN2HPGDMEN1
SCHEMBL16307929 0.80 SLC18A3 (0.49) SLC18A3TSHRALDH1A1SMN1; SMN2HPGD
SCHEMBL16789235 0.78 SLC18A3 (0.36) SLC18A3TSHRALDH1A1MEN1KMT2A
SCHEMBL16789236 0.73 HSD17B10 (0.43) TSHRALDH1A1HPGDMEN1KMT2A
SCHEMBL26828145 0.72 SLC18A3 (0.39) SLC18A3TSHRALDH1A1SMN1; SMN2HPGD
SCHEMBL26828141 0.71 TSHR (0.40) SLC18A3TSHRALDH1A1SMN1; SMN2HPGD
SCHEMBL22781105 0.70 ALDH1A1 (0.44) TSHRALDH1A1SMN1; SMN2HPGDMEN1
SCHEMBL16789226 0.70 SLC18A3 (0.43) SLC18A3TSHRALDH1A1SMN1; SMN2MEN1
SCHEMBL20283585 0.69 AR (0.51) SLC18A3TSHRALDH1A1SMN1; SMN2HPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10541260-B2 Organic photoelectric conversion element, optical area sensor, imaging device, and imaging apparatus CANON KABUSHIKI KAISHA (JP) 2020-01-21 US disclosed
US-20180108691-A1 ORGANIC PHOTOELECTRIC CONVERSION ELEMENT, OPTICAL AREA SENSOR, IMAGING DEVICE, AND IMAGING APPARATUS CANON KABUSHIKI KAISHA (JP) 2018-04-19 US disclosed
US-20180108691-A1 ORGANIC PHOTOELECTRIC CONVERSION ELEMENT, OPTICAL AREA SENSOR, IMAGING DEVICE, AND IMAGING APPARATUS CANON KABUSHIKI KAISHA (JP) 2018-04-19 US disclosed
US-9846385-B2 Organic light emitting element and display device CANON KABUSHIKI KAISHA (JP) 2017-12-19 US disclosed
US-9846385-B2 Organic light emitting element and display device CANON KABUSHIKI KAISHA (JP) 2017-12-19 US disclosed
US-20150162549-A1 ORGANIC LIGHT EMITTING ELEMENT AND DISPLAY DEVICE CANON KABUSHIKI KAISHA (JP) 2015-06-11 US disclosed
US-20150162549-A1 ORGANIC LIGHT EMITTING ELEMENT AND DISPLAY DEVICE CANON KABUSHIKI KAISHA (JP) 2015-06-11 US disclosed