Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IKBKB | O14920 | 4/20 | 0.69 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.66 |
| ▸ | PPARG | P37231 | 1/20 | 0.66 |
| ▸ | NCOA2 | Q15596 | 1/20 | 0.66 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.66 |
| ▸ | SLC9A1 | P19634 | 1/20 | 0.63 |
| ▸ | TARBP2 | Q15633 | 3/20 | 0.61 |
| ▸ | GAA | P10253 | 2/20 | 0.58 |
| ▸ | POLB | P06746 | 2/20 | 0.56 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.53 |
| ▸ | TSHR | P16473 | 1/20 | 0.53 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.53 |
| ▸ | RAB9A | P51151 | 1/20 | 0.53 |
| ▸ | HPGD | P15428 | 1/20 | 0.52 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11622339 | 0.87 | IKBKB (0.74) | IKBKBKDM4EPPARGNCOA2HSD17B10 | |
| SCHEMBL2179708 | 0.86 | TARBP2 (0.64) | IKBKBKDM4EPPARGNCOA2HSD17B10 | |
| SCHEMBL11624302 | 0.85 | IKBKB (0.69) | IKBKBKDM4EPPARGNCOA2HSD17B10 | |
| SCHEMBL6583843 | 0.85 | POLB (0.64) | IKBKBKDM4EPPARGNCOA2HSD17B10 | |
| Hydrochloric Acid SCHEMBL11622676 | 0.85 | TARBP2 (0.62) | IKBKBKDM4EPPARGNCOA2HSD17B10 | |
| SCHEMBL11621589 | 0.84 | SLC9A1 (0.66) | IKBKBKDM4EPPARGNCOA2HSD17B10 | |
| SCHEMBL11622797 | 0.84 | IKBKB (0.70) | IKBKBKDM4EPPARGNCOA2HSD17B10 | |
| SCHEMBL11625522 | 0.84 | IKBKB (0.57) | IKBKBKDM4EPPARGNCOA2HSD17B10 | |
| SCHEMBL893186 | 0.83 | TARBP2 (0.61) | IKBKBKDM4EPPARGNCOA2HSD17B10 | |
| SCHEMBL11619063 | 0.83 | KDM4E (0.65) | IKBKBKDM4EPPARGNCOA2HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4072689-A | ANTIINFLAMMATORY AGENTS | GRUPPO LEPETIT S.P.A. (IT) | 1978-02-07 | — | — | US | claimed |
| EP-2609091-A1 | PHARMACEUTICALLY ACTIVE COMPOUNDS AS AXL INHIBITORS | Lead Discovery Center GmbH (DE) | 2013-07-03 | — | — | EP | disclosed |
| WO-2012028332-A1 | PHARMACEUTICALLY ACTIVE COMPOUNDS AS AXL INHIBITORS | LEAD DISCOVERY CENTER GMBH (DE) | 2012-03-08 | — | — | WO | disclosed |
| US-4072689-A | ANTIINFLAMMATORY AGENTS | GRUPPO LEPETIT S.P.A. (IT) | 1978-02-07 | — | — | US | disclosed |