Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2D6 | P10635 | 1/20 | 0.64 |
| ▸ | CHRM3 | P20309 | 9/20 | 0.63 |
| ▸ | CHRNA7 | P36544 | 2/20 | 0.58 |
| ▸ | BCHE | P06276 | 1/20 | 0.58 |
| ▸ | ACHE | P22303 | 1/20 | 0.58 |
| ▸ | CHRM2 | P08172 | 7/20 | 0.56 |
| ▸ | CHRM1 | P11229 | 7/20 | 0.56 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.55 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.54 |
| ▸ | TSHR | P16473 | 1/20 | 0.54 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16790937 | 1.00 | CYP2D6 (0.64) | CYP2D6CHRM3CHRNA7BCHEACHE | |
| SCHEMBL12847023 | 0.84 | CYP2D6 (0.51) | CYP2D6CHRM3CHRNA7BCHEACHE | |
| SCHEMBL7824078 | 0.81 | CYP2D6 (0.67) | CYP2D6CHRM3CHRNA7BCHEACHE | |
| SCHEMBL15147390 | 0.81 | CYP2D6 (0.67) | CYP2D6CHRM3CHRNA7BCHEACHE | |
| SCHEMBL7824082 | 0.81 | CYP2D6 (0.67) | CYP2D6CHRM3CHRNA7BCHEACHE | |
| SCHEMBL5741549 | 0.81 | CHRM3 (0.66) | CYP2D6CHRM3CHRNA7BCHEACHE | |
| SCHEMBL17294779 | 0.80 | CHRM3 (0.64) | CYP2D6CHRM3CHRNA7BCHEACHE | |
| SCHEMBL231103 | 0.80 | CHRM3 (0.64) | CYP2D6CHRM3CHRNA7BCHEACHE | |
| SCHEMBL17294693 | 0.80 | CHRM3 (0.64) | CYP2D6CHRM3CHRNA7BCHEACHE | |
| SCHEMBL17294695 | 0.80 | CHRM3 (0.64) | CYP2D6CHRM3CHRNA7BCHEACHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9145409-B2 | Benzhydryl derivatives | CHIESI FARMACEUTICI S.P.A (IT) | 2015-09-29 | — | — | US | disclosed |
| US-20150158857-A1 | BENZHYDRYL DERIVATIVES | CHIESI FARMACEUTICI S.P.A. (IT) | 2015-06-11 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150158857-A1 | BENZHYDRYL DERIVATIVES | PDE4A, PDE4B, PDE3A | CYP2D6 801/4885CHRM3 10/4885CHRNA7 123/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.