Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM3 | P20309 | 6/20 | 0.66 |
| ▸ | CHRNA7 | P36544 | 2/20 | 0.60 |
| ▸ | BCHE | P06276 | 1/20 | 0.60 |
| ▸ | ACHE | P22303 | 1/20 | 0.60 |
| ▸ | CHRM2 | P08172 | 5/20 | 0.59 |
| ▸ | CHRM1 | P11229 | 5/20 | 0.59 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.58 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.58 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.56 |
| ▸ | HTT | P42858 | 1/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.53 |
| ▸ | TSHR | P16473 | 1/20 | 0.53 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18557643 | 0.90 | CHRM3 (0.56) | CHRM3CHRNA7BCHEACHECHRM2 | |
| SCHEMBL9329438 | 0.88 | CHRM3 (0.54) | CHRM3CHRNA7BCHEACHECHRM2 | |
| SCHEMBL19049351 | 0.87 | CHRM3 (0.64) | CHRM3CHRNA7BCHEACHECHRM2 | |
| SCHEMBL17294778 | 0.87 | CHRM3 (0.64) | CHRM3CHRNA7BCHEACHECHRM2 | |
| SCHEMBL17301741 | 0.87 | CHRM3 (0.64) | CHRM3CHRNA7BCHEACHECHRM2 | |
| SCHEMBL17294693 | 0.87 | CHRM3 (0.64) | CHRM3CHRNA7BCHEACHECHRM2 | |
| SCHEMBL17294695 | 0.87 | CHRM3 (0.64) | CHRM3CHRNA7BCHEACHECHRM2 | |
| SCHEMBL17294694 | 0.87 | CHRM3 (0.64) | CHRM3CHRNA7BCHEACHECHRM2 | |
| SCHEMBL17294779 | 0.87 | CHRM3 (0.64) | CHRM3CHRNA7BCHEACHECHRM2 | |
| SCHEMBL2482949 | 0.86 | CHRM3 (0.63) | CHRM3CHRNA7BCHEACHECHRM2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1631569-A2 | QUINUCLIDINE DERIVATIVES BINDING TO MUCARINIC M3 RECEPTORS | Novartis AG (CH) | 2006-03-08 | — | — | EP | disclosed |
| WO-2004096800-A2 | QUINUCLIDINE DERIVATIVES BINDING TO MUCARINIC M3 RECEPTORS | NOVARTIS AG (CH) | 2004-11-11 | — | — | WO | disclosed |