Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRIA4 | P48058 | 3/20 | 0.64 |
| ▸ | FNTA | P49354 | 15/20 | 0.56 |
| ▸ | FNTB | P49356 | 15/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.56 |
| ▸ | MAPT | P10636 | 1/20 | 0.53 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.53 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.53 |
| ▸ | PRKCZ | Q05513 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16792215 | 0.88 | GRIA4 (0.61) | GRIA4FNTAFNTBKMT2AMAPT | |
| SCHEMBL16798048 | 0.86 | FNTA (0.63) | GRIA4FNTAFNTBKMT2AMAPT | |
| SCHEMBL16792008 | 0.85 | GRIA4 (0.58) | GRIA4FNTAFNTBKMT2AMAPT | |
| SCHEMBL5756967 | 0.85 | GRIA4 (0.62) | GRIA4FNTAFNTBKMT2AMAPT | |
| SCHEMBL16792046 | 0.84 | GRIA4 (0.52) | GRIA4FNTAFNTBKMT2AMAPT | |
| SCHEMBL16792247 | 0.83 | GRIA4 (0.67) | GRIA4FNTAFNTBKMT2A | |
| SCHEMBL16798063 | 0.82 | GRIA4 (0.55) | GRIA4FNTAFNTBKMT2AMAPT | |
| SCHEMBL16792138 | 0.81 | FNTA (0.82) | GRIA4FNTAFNTBKMT2A | |
| SCHEMBL10652875 | 0.81 | GRIA4 (0.74) | GRIA4FNTAFNTBKMT2A | |
| SCHEMBL6603961 | 0.80 | GRIA4 (0.62) | GRIA4FNTAFNTBKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2015089349-A1 | INHIBITION OF ISOPRENOID BIOSYNTHETIC PATHWAYS TO TREAT NEUROINFLAMMATORY DISORDERS | TABACZYNSKI DAVID A (US) | 2015-06-18 | — | — | WO | disclosed |
| WO-2015084721-A1 | INHIBITION OF ISOPRENOID BIOSYNTHETIC PATHWAYS TO TREAT AUTOIMMUNE DISORDERS | TABACZYNSKI DAVID A (US) | 2015-06-11 | — | — | WO | disclosed |