Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PABPC1 | P11940 | 1/20 | 0.65 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.58 |
| ▸ | POLB | P06746 | 2/20 | 0.54 |
| ▸ | HTT | P42858 | 3/20 | 0.50 |
| ▸ | HPGD | P15428 | 3/20 | 0.50 |
| ▸ | HIF1A | Q16665 | 3/20 | 0.50 |
| ▸ | MEN1 | O00255 | 2/20 | 0.50 |
| ▸ | LMNA | P02545 | 2/20 | 0.50 |
| ▸ | MAPT | P10636 | 2/20 | 0.50 |
| ▸ | ALOX12 | P18054 | 2/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.50 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.50 |
| ▸ | SLC22A1 | O15245 | 1/20 | 0.50 |
| ▸ | USP2 | O75604 | 1/20 | 0.50 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.50 |
| ▸ | HSPD1 | P10809 | 1/20 | 0.50 |
| ▸ | HSPA5 | P11021 | 1/20 | 0.50 |
| ▸ | IDO1 | P14902 | 1/20 | 0.50 |
| ▸ | CASP1 | P29466 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16795365 | 0.87 | PABPC1 (0.65) | PABPC1SLC2A1POLBHTTHPGD | |
| SCHEMBL29852256 | 0.82 | PABPC1 (0.72) | PABPC1SLC2A1HTTHPGDHIF1A | |
| SCHEMBL21945698 | 0.79 | PABPC1 (1.00) | PABPC1SLC2A1HTTHPGDHIF1A | |
| SCHEMBL11667911 | 0.77 | POLB (0.54) | PABPC1POLBHTTHPGDMEN1 | |
| SCHEMBL11782294 | 0.77 | MEN1 (0.64) | POLBHTTMEN1MAPTKMT2A | |
| SCHEMBL15535482 | 0.76 | PABPC1 (0.58) | PABPC1SLC2A1POLBHTTHPGD | |
| SCHEMBL1039759 | 0.76 | BCHE (0.50) | PABPC1POLBHTTHPGDMEN1 | |
| SCHEMBL28319065 | 0.76 | CYP2D6 (0.67) | PABPC1SLC2A1HTTHPGDHIF1A | |
| SCHEMBL14826626 | 0.75 | KDM4E (0.41) | PABPC1SLC2A1POLBHTTHPGD | |
| SCHEMBL3862346 | 0.75 | PABPC1 (0.66) | PABPC1SLC2A1HTTHPGDHIF1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2015086693-A1 | PYRAZOLOPYRIMIDIN-2-YL DERIVATIVES AS JAK INHIBITORS | ALMIRALL, S.A. (ES) | 2015-06-18 | — | — | WO | disclosed |