Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPRF | P10586 | 1/20 | 0.56 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.56 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.56 |
| ▸ | SCN1A | P35498 | 2/20 | 0.52 |
| ▸ | SCN2A | Q99250 | 2/20 | 0.52 |
| ▸ | SCN3A | Q9NY46 | 2/20 | 0.52 |
| ▸ | MEN1 | O00255 | 2/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.52 |
| ▸ | CARM1 | Q86X55 | 1/20 | 0.45 |
| ▸ | PRMT6 | Q96LA8 | 1/20 | 0.45 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.45 |
| ▸ | L3MBTL3 | Q96JM7 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 2/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.43 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.43 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27964590 | 0.84 | PTPN2 (0.71) | PTPRFPTPN2PTPN1SCN1ASCN2A | |
| SCHEMBL27517068 | 0.80 | PTPRF (0.67) | PTPRFPTPN2PTPN1SCN1ASCN2A | |
| SCHEMBL20913216 | 0.79 | SCN1A (0.50) | PTPRFPTPN2PTPN1SCN1ASCN2A | |
| SCHEMBL13169508 | 0.79 | PTPRF (0.65) | PTPRFPTPN2PTPN1SCN1ASCN2A | |
| SCHEMBL21541871 | 0.78 | MAPT (0.69) | PTPRFPTPN2PTPN1SCN1ASCN2A | |
| SCHEMBL3347314 | 0.78 | CCR5 (0.49) | KMT2AL3MBTL1POLBMAPTCYP2C9 | |
| SCHEMBL8549828 | 0.78 | CHRM2 (0.59) | SCN1ASCN2ASCN3AMEN1KMT2A | |
| SCHEMBL7413532 | 0.78 | PTPN2 (0.63) | PTPRFPTPN2PTPN1SCN1ASCN2A | |
| Hydrochloric Acid SCHEMBL8556272 | 0.77 | CHRM2 (0.58) | SCN1ASCN2ASCN3AMEN1KMT2A | |
| SCHEMBL4218547 | 0.77 | MEN1 (0.61) | SCN1ASCN2ASCN3AMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2015086693-A1 | PYRAZOLOPYRIMIDIN-2-YL DERIVATIVES AS JAK INHIBITORS | ALMIRALL, S.A. (ES) | 2015-06-18 | — | — | WO | disclosed |