Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 6/20 | 0.55 |
| ▸ | PPARA | Q07869 | 5/20 | 0.55 |
| ▸ | PTPN1 | P18031 | 4/20 | 0.53 |
| ▸ | TERT | O14746 | 3/20 | 0.53 |
| ▸ | PPARD | Q03181 | 3/20 | 0.53 |
| ▸ | TOP1 | P11387 | 3/20 | 0.53 |
| ▸ | MAPT | P10636 | 2/20 | 0.53 |
| ▸ | BLM | P54132 | 2/20 | 0.53 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.53 |
| ▸ | FABP4 | P15090 | 2/20 | 0.53 |
| ▸ | GMNN | O75496 | 1/20 | 0.53 |
| ▸ | USP2 | O75604 | 1/20 | 0.53 |
| ▸ | LMNA | P02545 | 1/20 | 0.53 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.53 |
| ▸ | POLB | P06746 | 1/20 | 0.53 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.53 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.53 |
| ▸ | APEX1 | P27695 | 1/20 | 0.53 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.53 |
| ▸ | RECQL | P46063 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1679555 | 1.00 | PPARG (0.55) | PPARGPPARAPTPN1TERTPPARD | |
| SCHEMBL10336765 | 0.93 | F7 (0.50) | PPARGPPARAPTPN1TERTPPARD | |
| SCHEMBL570620 | 0.86 | PPARG (0.53) | PPARGPPARAPTPN1TERTPPARD | |
| SCHEMBL3040382 | 0.84 | TAS1R3 (0.44) | PPARGPPARAPTPN1TERTMAPT | |
| SCHEMBL3040379 | 0.84 | TAS1R3 (0.44) | PPARGPPARAPTPN1TERTMAPT | |
| SCHEMBL30945460 | 0.83 | FASN (0.61) | PPARGPPARAPTPN1TERTPPARD | |
| SCHEMBL29364578 | 0.83 | PTPN1 (0.51) | PPARGPPARAPTPN1TERTPPARD | |
| SCHEMBL16541029 | 0.83 | PTPN1 (0.56) | PPARGPPARAPTPN1TERTPPARD | |
| SCHEMBL5158124 | 0.83 | PPARG (0.59) | PPARGPPARAPTPN1TERTPPARD | |
| SCHEMBL5158113 | 0.83 | PPARG (0.59) | PPARGPPARAPTPN1TERTPPARD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2308847-A1 | Substituted pyridines as inhibitors of dipeptidyl peptidase IV and their application for the treatment of diabetes and related diseases | EMC microcollections GmbH (DE) | 2011-04-13 | — | — | EP | disclosed |