Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | HCRTR2 | O43614 | 5/20 | 0.38 |
| ▸ | HCRTR1 | O43613 | 3/20 | 0.38 |
| ▸ | KDM1A | O60341 | 4/20 | 0.38 |
| ▸ | MAOA | P21397 | 4/20 | 0.38 |
| ▸ | MAOB | P27338 | 4/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.37 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.36 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.36 |
| ▸ | HTR2B | P41595 | 1/20 | 0.36 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.36 |
| ▸ | HTR1A | P08908 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16339688 | 0.86 | CYP3A4 (0.48) | CYP3A4MAPK1HCRTR2HCRTR1KDM1A | |
| SCHEMBL1940012 | 0.86 | CYP3A4 (0.48) | CYP3A4MAPK1HCRTR2HCRTR1KDM1A | |
| SCHEMBL17821191 | 0.86 | CYP3A4 (0.48) | CYP3A4MAPK1HCRTR2HCRTR1KDM1A | |
| SCHEMBL16377487 | 0.86 | CYP3A4 (0.48) | CYP3A4MAPK1HCRTR2HCRTR1KDM1A | |
| SCHEMBL13958487 | 0.86 | CYP3A4 (0.48) | CYP3A4MAPK1HCRTR2HCRTR1KDM1A | |
| SCHEMBL16339711 | 0.86 | CYP3A4 (0.48) | CYP3A4MAPK1HCRTR2HCRTR1KDM1A | |
| SCHEMBL17450295 | 0.77 | GABRP (0.34) | — | |
| SCHEMBL16070607 | 0.77 | GABRP (0.34) | — | |
| SCHEMBL16070600 | 0.77 | GABRP (0.34) | — | |
| SCHEMBL6704402 | 0.77 | CYP3A4 (0.46) | CYP3A4MAPK1HCRTR2HCRTR1KDM1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3079685-A1 | SULFAMATE DERIVATIVE COMPOUNDS FOR USE IN TREATING OR ALLEVIATING PAIN | Bio-Pharm Solutions Co., Ltd. (KR) | 2016-10-19 | — | — | EP | claimed |
| WO-2015088273-A1 | SULFAMATE DERIVATIVE COMPOUNDS FOR USE IN TREATING OR ALLEVIATING PAIN | BIO-PHARM SOLUTIONS, CO., LTD. (KR) | 2015-06-18 | — | — | WO | claimed |