Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR84 | Q9NQS5 | 7/20 | 0.64 |
| ▸ | FFAR1 | O14842 | 3/20 | 0.49 |
| ▸ | FFAR4 | Q5NUL3 | 2/20 | 0.49 |
| ▸ | FAAH | O00519 | 1/20 | 0.41 |
| ▸ | ZDHHC7 | Q9NXF8 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | LCK | P06239 | 1/20 | 0.40 |
| ▸ | PPARD | Q03181 | 1/20 | 0.40 |
| ▸ | ZDHHC20 | Q5W0Z9 | 1/20 | 0.40 |
| ▸ | ZDHHC2 | Q9UIJ5 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | GMNN | O75496 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.39 |
| ▸ | BLM | P54132 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1679076 | 1.00 | GPR84 (0.64) | GPR84FFAR1FFAR4FAAHZDHHC7 | |
| SCHEMBL1679074 | 1.00 | GPR84 (0.64) | GPR84FFAR1FFAR4FAAHZDHHC7 | |
| SCHEMBL21722671 | 1.00 | GPR84 (0.64) | GPR84FFAR1FFAR4FAAHZDHHC7 | |
| SCHEMBL23723113 | 0.84 | GPR84 (0.58) | GPR84FFAR1FFAR4ZDHHC7MAPT | |
| SCHEMBL20472006 | 0.84 | GPR84 (0.58) | GPR84FFAR1FFAR4ZDHHC7MAPT | |
| SCHEMBL20471823 | 0.84 | GPR84 (0.58) | GPR84FFAR1FFAR4ZDHHC7MAPT | |
| SCHEMBL12371513 | 0.84 | GPR84 (0.58) | GPR84FFAR1FFAR4ZDHHC7MAPT | |
| SCHEMBL28590845 | 0.84 | GPR84 (0.58) | GPR84FFAR1FFAR4ZDHHC7MAPT | |
| SCHEMBL28183600 | 0.83 | GPR84 (0.55) | GPR84FFAR1FFAR4ZDHHC7MAPT | |
| SCHEMBL9156938 | 0.81 | GPR84 (0.81) | GPR84FFAR1FFAR4FAAHMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8765431-B2 | Method for enzymatic production of decarboxylated polyketides and fatty acids | THE REGENTS OF THE UNIVERSITY OF MICHIGAN (US) | 2014-07-01 | — | — | US | disclosed |
| US-8765431-B2 | Method for enzymatic production of decarboxylated polyketides and fatty acids | THE REGENTS OF THE UNIVERSITY OF MICHIGAN (US) | 2014-07-01 | — | — | US | disclosed |
| US-8765431-B2 | Method for enzymatic production of decarboxylated polyketides and fatty acids | THE REGENTS OF THE UNIVERSITY OF MICHIGAN (US) | 2014-07-01 | — | — | US | disclosed |
| US-20110091952-A1 | METHOD FOR ENZYMATIC PRODUCTION OF DECARBOXYLATED POLYKETIDES AND FATTY ACIDS | THE REGENTS OF THE UNIVERSITY OF MICHIGAN (US) | 2011-04-21 | — | — | US | disclosed |
| US-20110091952-A1 | METHOD FOR ENZYMATIC PRODUCTION OF DECARBOXYLATED POLYKETIDES AND FATTY ACIDS | THE REGENTS OF THE UNIVERSITY OF MICHIGAN (US) | 2011-04-21 | — | — | US | disclosed |
| US-20110091952-A1 | METHOD FOR ENZYMATIC PRODUCTION OF DECARBOXYLATED POLYKETIDES AND FATTY ACIDS | THE REGENTS OF THE UNIVERSITY OF MICHIGAN (US) | 2011-04-21 | — | — | US | disclosed |
| WO-2011011689-A2 | METHOD FOR ENZYMATIC PRODUCTION OF DECARBOXYLATED POLYKETIDES AND FATTY ACIDS | THE REGENTS OF THE UNIVERSITY OF MICHIGAN (US) | 2011-01-27 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110091952-A1 | METHOD FOR ENZYMATIC PRODUCTION OF DECARBOXYLATED POLYKETIDES AND FATTY ACIDS | STS, COASY, SCD | GPR84 2223/4885FFAR1 273/4885FFAR4 388/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.