Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.58 |
| ▸ | CNR1 | P21554 | 1/20 | 0.58 |
| ▸ | CNR2 | P34972 | 1/20 | 0.58 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2147225 | 1.00 | ALDH1A1 (0.58) | ALDH1A1CNR1CNR2KDM4E | |
| SCHEMBL30296927 | 0.95 | ALDH1A1 (0.54) | ALDH1A1CNR1CNR2 | |
| SCHEMBL12462551 | 0.95 | ALDH1A1 (0.50) | ALDH1A1CNR1CNR2 | |
| SCHEMBL14715825 | 0.84 | ALDH1A1 (0.68) | ALDH1A1CNR1CNR2 | |
| SCHEMBL14715826 | 0.84 | ALDH1A1 (0.68) | ALDH1A1CNR1CNR2 | |
| SCHEMBL18923368 | 0.84 | ALDH1A1 (0.68) | ALDH1A1CNR1CNR2 | |
| SCHEMBL2176259 | 0.84 | ALDH1A1 (0.62) | ALDH1A1CNR1CNR2 | |
| SCHEMBL2176257 | 0.84 | ALDH1A1 (0.62) | ALDH1A1CNR1CNR2 | |
| SCHEMBL14834026 | 0.84 | ALDH1A1 (0.62) | ALDH1A1CNR1CNR2 | |
| SCHEMBL16902071 | 0.83 | ALDH1A1 (0.65) | ALDH1A1CNR1CNR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3286318-A2 | SARNA COMPOSITIONS AND METHODS OF USE | Mina Therapeutics Limited (GB) | 2018-02-28 | — | — | EP | disclosed |
| EP-3076994-A2 | TARGETED ADAPTIVE VACCINES | Moderna Therapeutics, Inc. (US) | 2016-10-12 | — | — | EP | disclosed |
| WO-2015085318-A2 | TARGETED ADAPTIVE VACCINES | MODERNA THERAPEUTICS, INC. (US) | 2015-06-11 | — | — | WO | disclosed |