Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 7/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.51 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.51 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | TP53 | P04637 | 3/20 | 0.40 |
| ▸ | HIF1A | Q16665 | 3/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | THRB | P10828 | 2/20 | 0.35 |
| ▸ | ATM | Q13315 | 1/20 | 0.32 |
| ▸ | HCAR2 | Q8TDS4 | 2/20 | 0.31 |
| ▸ | BBOX1 | O75936 | 2/20 | 0.30 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16798997 | 0.99 | TSHR (0.54) | TSHRALDH1A1CYP3A4HPGDTP53 | |
| SCHEMBL16799080 | 0.99 | TSHR (0.54) | TSHRALDH1A1CYP3A4HPGDTP53 | |
| Water SCHEMBL15390901 | 0.99 | TSHR (0.50) | TSHRALDH1A1CYP3A4HPGDTP53 | |
| SCHEMBL16799088 | 0.99 | TSHR (0.54) | TSHRALDH1A1CYP3A4HPGDTP53 | |
| SCHEMBL16799000 | 0.99 | TSHR (0.54) | TSHRALDH1A1CYP3A4HPGDTP53 | |
| Water SCHEMBL28062412 | 0.96 | TSHR (0.47) | TSHRALDH1A1CYP3A4HPGDTP53 | |
| Water SCHEMBL15389563 | 0.96 | TSHR (0.50) | TSHRALDH1A1CYP3A4HPGDTP53 | |
| SCHEMBL35504 | 0.95 | TSHR (0.49) | TSHRALDH1A1CYP3A4HPGDTP53 | |
| Water SCHEMBL15389828 | 0.94 | TSHR (0.53) | TSHRALDH1A1CYP3A4HPGDTP53 | |
| Water SCHEMBL15389728 | 0.94 | TSHR (0.53) | TSHRALDH1A1CYP3A4HPGDTP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3077476-B1 | NANOCRYSTALS COMPLEXED WITH FUNCTIONALIZABLE ENHANCED AFFINITY LIGANDS AND USE THEREOF | NEXDOT (FR) | 2020-02-12 | — | — | EP | disclosed |
| US-10465030-B2 | Nanoparticles complexed with functionalizable enhanced affinity ligands and use thereof | NEXDOT (FR) | 2019-11-05 | — | — | US | disclosed |
| US-20160304648-A1 | NANOPARTICLES COMPLEXED WITH FUNCTIONALIZABLE ENHANCED AFFINITY LIGANDS AND USE THEREOF | NEXDOT (FR) | 2016-10-20 | — | — | US | disclosed |
| EP-3077476-A1 | NANOPARTICLES COMPLEXED WITH FUNCTIONALIZABLE ENHANCED AFFINITY LIGANDS AND USE THEREOF | Nexdot (FR) | 2016-10-12 | — | — | EP | disclosed |
| WO-2015082656-A1 | NANOPARTICLES COMPLEXED WITH FUNCTIONALIZABLE ENHANCED AFFINITY LIGANDS AND USE THEREOF | NEXDOT (FR) | 2015-06-11 | — | — | WO | disclosed |