Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 7/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.49 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.49 |
| ▸ | HPGD | P15428 | 1/20 | 0.49 |
| ▸ | TP53 | P04637 | 3/20 | 0.41 |
| ▸ | HIF1A | Q16665 | 3/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | THRB | P10828 | 2/20 | 0.36 |
| ▸ | ATM | Q13315 | 1/20 | 0.33 |
| ▸ | BBOX1 | O75936 | 4/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Water SCHEMBL15390669 | 0.98 | TSHR (0.47) | TSHRALDH1A1CYP3A4HPGDTP53 | |
| SCHEMBL16799374 | 0.95 | TSHR (0.51) | TSHRALDH1A1CYP3A4HPGDTP53 | |
| Water SCHEMBL15390901 | 0.94 | TSHR (0.50) | TSHRALDH1A1CYP3A4HPGDTP53 | |
| SCHEMBL16798997 | 0.94 | TSHR (0.54) | TSHRALDH1A1CYP3A4HPGDTP53 | |
| SCHEMBL16799251 | 0.94 | TSHR (0.50) | TSHRALDH1A1CYP3A4HPGDTP53 | |
| SCHEMBL16799088 | 0.94 | TSHR (0.54) | TSHRALDH1A1CYP3A4HPGDTP53 | |
| SCHEMBL16799363 | 0.94 | TSHR (0.50) | TSHRALDH1A1CYP3A4HPGDTP53 | |
| SCHEMBL16798962 | 0.94 | TSHR (0.50) | TSHRALDH1A1CYP3A4HPGDTP53 | |
| SCHEMBL16798843 | 0.94 | TSHR (0.50) | TSHRALDH1A1CYP3A4HPGDTP53 | |
| SCHEMBL16799000 | 0.94 | TSHR (0.54) | TSHRALDH1A1CYP3A4HPGDTP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 273 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3481897-B9 | SILICONE HYDROGELS COMPRISING POLYAMIDES | JOHNSON & JOHNSON VISION CARE (US) | 2024-04-10 | — | — | EP | claimed |
| EP-3481897-B1 | SILICONE HYDROGELS COMPRISING POLYAMIDES | JOHNSON & JOHNSON VISION CARE (US) | 2024-01-03 | — | — | EP | claimed |
| US-11828913-B2 | Silicone hydrogels comprising polyamides | JOHNSON & JOHNSON VISION CARE, INC. (US) | 2023-11-28 | — | — | US | claimed |
| US-20210141122-A1 | SILICONE HYDROGELS COMPRISING POLYAMIDES | JOHNSON & JOHNSON VISION CARE (US) | 2021-05-13 | — | — | US | claimed |
| US-10890689-B2 | Silicone hydrogels comprising polyamides | JOHNSON & JOHNSON VISION CARE, INC. (US) | 2021-01-12 | — | — | US | claimed |
| US-20190317248-A1 | SILICONE HYDROGELS COMPRISING POLYAMIDES | JOHNSON & JOHNSON VISION CARE (US) | 2019-10-17 | — | — | US | claimed |
| US-10371865-B2 | Silicone hydrogels comprising polyamides | JOHNSON & JOHNSON VISION CARE, INC. (US) | 2019-08-06 | — | — | US | claimed |
| EP-3401342-A1 | POLYMERS AND NANOGEL MATERIALS AND METHODS FOR MAKING AND USING THE SAME | Johnson & Johnson Vision Care, Inc. (US) | 2018-11-14 | — | — | EP | claimed |
| US-10073192-B2 | Polymers and nanogel materials and methods for making and using the same | JOHNSON & JOHNSON VISION CARE, INC. (US) | 2018-09-11 | — | — | US | claimed |
| US-20180011222-A1 | SILICONE HYDROGELS COMPRISING POLYAMIDES | JOHNSON & JOHNSON VISION CARE, INC. | 2018-01-11 | — | — | US | claimed |
| US-9617423-B2 | Macroinitiator containing hydrophobic segment | JOHNSON & JOHNSON VISION CARE, INC. (US) | 2017-04-11 | — | — | US | claimed |
| US-20160194497-A1 | MACROINITIATOR CONTAINING HYDROPHOBIC SEGMENT | JOHNSON & JOHNSON VISION CARE (US) | 2016-07-07 | — | — | US | claimed |
| EP-2855544-A2 | POLYMERS AND NANOGEL MATERIALS AND METHODS FOR MAKING AND USING THE SAME | Johnson & Johnson Vision Care Inc. (US) | 2015-04-08 | — | — | EP | claimed |
| WO-2013176886-A2 | POLYMERS AND NANOGEL MATERIALS AND METHODS FOR MAKING AND USING THE SAME | JOHNSON & JOHNSON VISION CARE, INC. (US) | 2013-11-28 | — | — | WO | claimed |
| US-20130317131-A1 | POLYMERS AND NANOGEL MATERIALS AND METHODS FOR MAKING AND USING THE SAME | JOHNSON & JOHNSON VISION CARE, INC. (US) | 2013-11-28 | — | — | US | claimed |
| US-12638613-B2 | Ophthalmic lenses and their manufacture by in-mold modification | JOHNSON & JOHNSON VISION CARE, INC. (US) | 2026-05-26 | — | — | US | disclosed |
| US-12624214-B2 | Polymerizable absorbers of UV and high energy visible light | JOHNSON & JOHNSON VISION CARE, INC. (US) | 2026-05-12 | — | — | US | disclosed |
| WO-2011140318-A1 | NON-REACTIVE, HYDROPHILIC POLYMERS HAVING TERMINAL SILOXANES AND USES OF THE SAME | JOHNSON & JOHNSON VISION CARE, INC. (US) | 2011-11-10 | — | — | WO | disclosed |
| US-7923428-B2 | Composition for cleaning or rinsing hard surfaces | RHODIA CHIMIE (FR) | 2011-04-12 | — | — | US | disclosed |
| US-7923428-B2 | Composition for cleaning or rinsing hard surfaces | RHODIA CHIMIE (FR) | 2011-04-12 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-12638613-B2 | Ophthalmic lenses and their manufacture by in-mold modification | UACA, AXL, CRYZ | TSHR 2482/4885ALDH1A1 1768/4885CYP3A4 1323/4885 |
| US-12624214-B2 | Polymerizable absorbers of UV and high energy visible light | CRY1, SCNN1G, MALT1 | TSHR 832/4885ALDH1A1 1349/4885CYP3A4 679/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.