Known targets — ChEMBL curated mechanism
ADRA2AADRA2BADRA2CADRB2AGTR1AVPR1AAVPR1BAVPR2BDKRB2CALCRCHRNA3CHRNB4ESR1ESR2GHSRGNRHRGSC1HSPA8MALT1MC1RMC4RNOS1NOS2NOS3OPRK1OXTRRAMP1RAMP2RAMP3SCN5ASSTR1SSTR2SSTR3SSTR4SSTR5dacAdacBdacCfolPftsImrcAmrcBmrdArplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of 1,4-Butanediol. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR3 | O14843 | 2/20 | 0.54 |
| ▸ | LCK | P06239 | 1/20 | 0.54 |
| ▸ | FYN | P06241 | 1/20 | 0.54 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.53 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.53 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.53 |
| ▸ | CAMK2A | Q9UQM7 | 1/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.47 |
| ▸ | LMNA | P02545 | 4/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | FNTA | P49354 | 1/20 | 0.39 |
| ▸ | FNTB | P49356 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | SLC15A2 | Q16348 | 1/20 | 0.35 |
| ▸ | CYP4F2 | P78329 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| 1,4-Butanediol SCHEMBL3332310 | 1.00 | FFAR3 (0.54) | FFAR3LCKFYNGPR84FFAR1 | |
| 1,4-Butanediol SCHEMBL28269711 | 1.00 | FFAR3 (0.54) | FFAR3LCKFYNGPR84FFAR1 | |
| Acetic Acid SCHEMBL28557074 | 0.96 | GPR84 (0.58) | FFAR3LCKFYNGPR84FFAR1 | |
| Acetic Acid SCHEMBL11291740 | 0.96 | GPR84 (0.58) | FFAR3LCKFYNGPR84FFAR1 | |
| 1,6-Hexanediol SCHEMBL28434993 | 0.96 | GPR84 (0.58) | FFAR3LCKFYNGPR84FFAR1 | |
| 1,5-Pentanediol SCHEMBL6419062 | 0.96 | GPR84 (0.58) | FFAR3LCKFYNGPR84FFAR1 | |
| 1,4-Butanediol SCHEMBL29227335 | 0.96 | FFAR3 (0.50) | FFAR3LCKFYNGPR84FFAR1 | |
| 1,5-Pentanediol SCHEMBL5373304 | 0.96 | GPR84 (0.58) | FFAR3LCKFYNGPR84FFAR1 | |
| Acetic Acid SCHEMBL11292613 | 0.96 | GPR84 (0.58) | FFAR3LCKFYNGPR84FFAR1 | |
| 1,6-Hexanediol SCHEMBL27886625 | 0.96 | GPR84 (0.58) | FFAR3LCKFYNGPR84FFAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 137 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4441021-B1 | 1,3-BUTANEDIOL PURIFIED FROM A MIXTURE OF DIOLS | NOVAMONT SPA (IT) | 2026-01-28 | — | — | EP | claimed |
| US-20250019331-A1 | 1,3-BUTANEDIOL PURIFIED FROM A MIXTURE OF DIOLS | NOVAMONT S.P.A. (IT) | 2025-01-16 | — | — | US | claimed |
| EP-4441021-A1 | 1,3-BUTANEDIOL PURIFIED FROM A MIXTURE OF DIOLS | Novamont S.p.A. (IT) | 2024-10-09 | — | — | EP | claimed |
| US-20240240106-A1 | 1,4-BUTANEDIOL MONO- OR DIESTERS FOR USE AS AROMA CHEMICALS | BASF SE (DE) | 2024-07-18 | — | — | US | claimed |
| CN-117396586-A | 1, 4-butanediol mono-or diesters as fragrance chemicals | 巴斯夫欧洲公司 | 2024-01-12 | — | — | CN | claimed |
| WO-2023099650-A1 | 1,3-BUTANEDIOL PURIFIED FROM A MIXTURE OF DIOLS | NOVAMONT S.P.A. (IT) | 2023-06-08 | — | — | WO | claimed |
| CN-108047356-B | Method for refining eucommia ulmoides crude glue solution | 山东贝隆杜仲生物工程有限公司 | 2020-06-16 | — | — | CN | claimed |
| EP-0797644-B1 | REMOVABLE PRESSURE SENSITIVE ADHESIVE AND ARTICLE | MINNESOTA MINING & MFG (US) | 2002-05-22 | — | — | EP | claimed |
| US-5300202-A | Dissociating the gases by pyrolysis using electromagnetic waves | MOEGEL HELMUT (DE) | 1994-04-05 | — | — | US | claimed |
| EP-0489078-B1 | PROCESS AND DEVICE FOR DISPOSING OF ORGANIC VAPOURS, IN PARTICULAR SOLVENT VAPOURS | Mögel, Helmut (DE) | 1993-08-04 | — | — | EP | claimed |
| EP-0136033-A2 | Pour-on formulation for the control of parasites | ICI AUSTRALIA LIMITED (AU) | 1985-04-03 | — | — | EP | claimed |
| JP-7053424-A | — | — | None | — | — | JP | disclosed |
| JP-52095655-A | — | — | None | — | — | JP | disclosed |
| EP-4441021-B1 | 1,3-BUTANEDIOL PURIFIED FROM A MIXTURE OF DIOLS | NOVAMONT SPA (IT) | 2026-01-28 | — | — | EP | disclosed |
| CN-110297397-B | Photosensitive composition, composite, electronic component, and method for producing electronic component | 则武株式会社 | 2025-02-25 | — | — | CN | disclosed |
| US-4435587-A | REACTION OF A SILICON HALIDE COMPOUND WITH AN ISOCYANATE OR CYANATE | MATSUMOTO SEIYAKU KOGYO KABUSHIKI KAISHA (JP) | 1984-03-06 | — | — | US | disclosed |
| JP-S5295655-A | PREPARATION OF CYCLIC ETHERS | MITSUBISHI CHEM IND LTD | 1977-08-11 | — | — | JP | disclosed |
| US-4010171-A | Process for preparing tetrahydrofuran | GENERAL ELECTRIC COMPANY (US) | 1977-03-01 | — | — | US | disclosed |
| US-4005113-A | Multi-step process for preparation of tetrahydrofuran starting from propylene, oxygen and a carboxylic acid | GENERAL ELECTRIC COMPANY (US) | 1977-01-25 | — | — | US | disclosed |
| US-4005112-A | ZEOLITE CATALYST | GENERAL ELECTRIC COMPANY (US) | 1977-01-25 | — | — | US | disclosed |