Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRM1 | P35372 | 1/20 | 0.57 |
| ▸ | CA12 | O43570 | 3/20 | 0.52 |
| ▸ | CA1 | P00915 | 3/20 | 0.52 |
| ▸ | CA2 | P00918 | 3/20 | 0.52 |
| ▸ | CA9 | Q16790 | 3/20 | 0.52 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.49 |
| ▸ | LYPLA2 | O95372 | 1/20 | 0.48 |
| ▸ | PKM | P14618 | 1/20 | 0.48 |
| ▸ | SENP1 | Q9P0U3 | 1/20 | 0.47 |
| ▸ | MAP1B | P46821 | 1/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.45 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.45 |
| ▸ | FOLH1 | Q04609 | 3/20 | 0.44 |
| ▸ | SETD7 | Q8WTS6 | 1/20 | 0.43 |
| ▸ | KDM1A | O60341 | 2/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22368146 | 1.00 | OPRM1 (0.57) | OPRM1CA12CA1CA2CA9 | |
| SCHEMBL22368122 | 0.96 | OPRM1 (0.57) | OPRM1CA12CA1CA2CA9 | |
| SCHEMBL16801317 | 0.96 | OPRM1 (0.57) | OPRM1CA12CA1CA2CA9 | |
| SCHEMBL23153094 | 0.92 | OPRM1 (0.57) | OPRM1CA12CA1CA2CA9 | |
| SCHEMBL22368144 | 0.92 | OPRM1 (0.57) | OPRM1CA12CA1CA2CA9 | |
| SCHEMBL23153092 | 0.89 | OPRM1 (0.57) | OPRM1CA12CA1CA2CA9 | |
| SCHEMBL23153093 | 0.88 | OPRM1 (0.57) | OPRM1CA12CA1CA2CA9 | |
| SCHEMBL22368116 | 0.85 | OPRM1 (0.51) | OPRM1CA12CA1CA2CA9 | |
| SCHEMBL16801315 | 0.85 | OPRM1 (0.51) | OPRM1CA12CA1CA2CA9 | |
| SCHEMBL18133043 | 0.83 | OPRM1 (0.44) | OPRM1CA12CA1CA2CA9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11912989-B2 | Antigen-binding molecules, the antigen-binding activity of which varies according to the concentration of compounds, and libraries of said molecules | CHUGAI SEIYAKU KABUSHIKI KAISHA (JP) | 2024-02-27 | — | — | US | disclosed |
| US-20210180049-A1 | ANTIGEN-BINDING MOLECULES, THE ANTIGEN-BINDING ACTIVITY OF WHICH VARIES ACCORDING TO THE CONCENTRATION OF COMPOUNDS, AND LIBRARIES OF SAID MOLECULES | CHUGAI SEIYAKU KABUSHIKI KAISHA (JP) | 2021-06-17 | — | — | US | disclosed |
| US-10961530-B2 | Antigen-binding molecules, the antigen-binding activity of which varies according to the concentration of compounds, and libraries of said molecules | CHUGAI SEIYAKU KABUSHIKI KAISHA (JP) | 2021-03-30 | — | — | US | disclosed |
| US-20160304862-A1 | ANTIGEN-BINDING MOLECULES, THE ANTIGEN-BINDING ACTIVITY OF WHICH VARIES ACCORDING TO THE CONCENTRATION OF COMPOUNDS, AND LIBRARIES OF SAID MOLECULES | CHUGAI SEIYAKU KABUSHIKI KAISHA (JP) | 2016-10-20 | — | — | US | disclosed |
| EP-3078744-A1 | ANTIGEN-BINDING MOLECULES, THE ANTIGEN-BINDING ACTIVITY OF WHICH VARIES ACCORDING TO THE CONCENTRATION OF COMPOUNDS, AND LIBRARIES OF SAID MOLECULES | Chugai Seiyaku Kabushiki Kaisha (JP) | 2016-10-12 | — | — | EP | disclosed |
| WO-2015083764-A1 | ANTIGEN-BINDING MOLECULES, THE ANTIGEN-BINDING ACTIVITY OF WHICH VARIES ACCORDING TO THE CONCENTRATION OF COMPOUNDS, AND LIBRARIES OF SAID MOLECULES | 中外製薬株式会社 | 2015-06-11 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210180049-A1 | ANTIGEN-BINDING MOLECULES, THE ANTIGEN-BINDING ACTIVITY OF WHICH VARIES ACCORDING TO THE CONCENTRATION OF COMPOUNDS, AND LIBRARIES OF SAID MOLECULES | MICA, CD69, CD74 | OPRM1 3199/4885CA12 167/4885CA1 550/4885 |
| US-11912989-B2 | Antigen-binding molecules, the antigen-binding activity of which varies according to the concentration of compounds, and libraries of said molecules | MICA, CD69, CD74 | OPRM1 3199/4885CA12 167/4885CA1 550/4885 |
| US-20160304862-A1 | ANTIGEN-BINDING MOLECULES, THE ANTIGEN-BINDING ACTIVITY OF WHICH VARIES ACCORDING TO THE CONCENTRATION OF COMPOUNDS, AND LIBRARIES OF SAID MOLECULES | MICA, CD69, CD74 | OPRM1 3199/4885CA12 167/4885CA1 550/4885 |
| US-10961530-B2 | Antigen-binding molecules, the antigen-binding activity of which varies according to the concentration of compounds, and libraries of said molecules | MICA, CD69, CD74 | OPRM1 3199/4885CA12 167/4885CA1 550/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.