SCHEMBL1680158

SCHEMBL1680158

C=CC(C)NC=O

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10656483 0.75
SCHEMBL3348272 0.75
SCHEMBL8519756 0.75
SCHEMBL6036724 0.75
SCHEMBL2615231 0.74
SCHEMBL8532399 0.69
SCHEMBL6674862 0.69
SCHEMBL16421168 0.69
SCHEMBL1917 0.67
SCHEMBL6435190 0.67

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 116 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3861039-A1 HYDROGEL COMPOSITIONS Ophtalmic Compagnie (FR) 2021-08-11 EP claimed
WO-2020070423-A1 HYDROGEL COMPOSITIONS OPHTALMIC COMPAGNIE (FR) 2020-04-09 WO claimed
CN-106459308-B Silicone acrylamide copolymers 庄臣及庄臣视力保护公司 2019-11-15 CN claimed
CN-110100202-A With the contact lenses for being incorporated to component 库柏维景国际控股公司 2019-08-06 CN claimed
CN-109790353-A SILICONE HYDROGELS COMPRISING POLYAMIDES 庄臣及庄臣视力保护公司 2019-05-21 CN claimed
CN-109689714-A Silicone hydrogels comprising N-alkylmethacrylamides and contact lenses made therefrom 庄臣及庄臣视力保护公司 2019-04-26 CN claimed
CN-109415474-A SILICONE HYDROGELS COMPRISING HIGH LEVELS OF POLYAMIDES 庄臣及庄臣视力保护公司 2019-03-01 CN claimed
CN-109073783-A Manufacture the method with the silicone hydrogel contact lenses of reduced evaporation rate 库柏维景国际控股公司 2018-12-21 CN claimed
CN-104114612-B Silicone hydrogels containing desirable water content and oxygen permeability 庄臣及庄臣视力保护公司 2017-09-26 CN claimed
CN-104144972-B Ionic silicone hydrogels 庄臣及庄臣视力保护公司 2017-07-21 CN claimed
CN-104144971-B Silicone hydrogels formed from zero diluent reactive mixtures 庄臣及庄臣视力保护公司 2017-03-15 CN claimed
CN-106459308-A Silicone acrylamide copolymers 庄臣及庄臣视力保护公司 2017-02-22 CN claimed
CN-106459309-A Silicone acrylamide copolymers 庄臣及庄臣视力保护公司 2017-02-22 CN claimed
CN-103502317-B Macroinitiators containing hydrophobic segments 庄臣及庄臣视力保护公司 2017-02-08 CN claimed
EP-2632455-A1 OPHTHALMIC COMPOSITIONS Johnson & Johnson Vision Care Inc. (US) 2013-09-04 EP claimed
EP-2552977-A1 MULTIPLE FUNCTION GRAFT POLYMER Castrol Limited (GB) 2013-02-06 EP claimed
WO-2012058224-A1 OPHTHALMIC COMPOSITIONS JOHNSON & JOHNSON VISION CARE, INC. (US) 2012-05-03 WO claimed
WO-2011123408-A1 MULTIPLE FUNCTION GRAFT POLYMER CASTROL LIMITED (GB) 2011-10-06 WO claimed
EP-1874837-A1 MULTIPLE-FUNCTION DISPERSANT GRAFT POLYMER CASTROL LIMITED (GB) 2008-01-09 EP claimed
WO-2006116663-A1 MULTIPLE-FUNCTION DISPERSANT GRAFT POLYMER CASTROL LIMITED (GB) 2006-11-02 WO claimed