⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3348272 | 1.00 | — | — | |
| SCHEMBL10656483 | 1.00 | — | — | |
| SCHEMBL1680158 | 0.75 | — | — | |
| SCHEMBL10420937 | 0.72 | ADH1B (0.37) | — | |
| SCHEMBL6435190 | 0.72 | — | — | |
| SCHEMBL1917 | 0.72 | — | — | |
| SCHEMBL11156551 | 0.72 | ADH1B (0.62) | — | |
| SCHEMBL28825344 | 0.72 | — | — | |
| SCHEMBL23259545 | 0.71 | — | — | |
| SCHEMBL3132758 | 0.69 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1713806-A1 | COMPOUNDS AND COMPOSITIONS AS PROTEIN KINASE INHIBITORS | IRM, LLC (BM) | 2006-10-25 | — | — | EP | claimed |
| WO-2005107760-A1 | COMPOUNDS AND COMPOSITIONS AS INDUCERS OF KERATINOCYTE DIFFERENTIATION | IRM LLC (BM) | 2005-11-17 | — | — | WO | claimed |
| WO-2005080393-A1 | COMPOUNDS AND COMPOSITIONS AS PROTEIN KINASE INHIBITORS | IRM LLC (BM) | 2005-09-01 | — | — | WO | claimed |
| US-6740774-B1 | REACTING CARBOXAMIDE WITH GLYOXAL MONOACETAL DERIVATIVE | BASF AKTIENGESELLSCHAFT (DE) | 2004-05-25 | — | — | US | claimed |
| EP-1078916-B1 | Process for the preparation of N-acylaminoacid esters and N-acylaminoacetals | BASF AG (DE) | 2002-12-11 | — | — | EP | claimed |
| WO-2016149501-A2 | MODIFIED THERAPEUTIC AGENTS AND COMPOSITIONS THEREOF | THE CALIFORNIA INSTITUTE FOR BIOMEDICAL RESEARCH (US) | 2016-09-22 | — | — | WO | disclosed |
| US-7173041-B2 | Polyglutamic acid-camptothecin conjugates and methods of preparation | CELL THERAPEUTICS INC. (US) | 2007-02-06 | — | — | US | disclosed |
| EP-1713806-A1 | COMPOUNDS AND COMPOSITIONS AS PROTEIN KINASE INHIBITORS | IRM, LLC (BM) | 2006-10-25 | — | — | EP | disclosed |
| WO-2005107760-A1 | COMPOUNDS AND COMPOSITIONS AS INDUCERS OF KERATINOCYTE DIFFERENTIATION | IRM LLC (BM) | 2005-11-17 | — | — | WO | disclosed |
| WO-2005080393-A1 | COMPOUNDS AND COMPOSITIONS AS PROTEIN KINASE INHIBITORS | IRM LLC (BM) | 2005-09-01 | — | — | WO | disclosed |
| US-5556829-A | AMIDES, SULFONAMIDES, PHOSPHOAMIDES, AGRICULTURAL USE | ZAMBON GROUP S.P.A. (IT) | 1996-09-17 | — | — | US | disclosed |
| EP-0454067-B1 | Compositions having herbicidal activity containing N-Alkyl-amides as active ingredient | ZAMBON SPA (IT) | 1995-09-27 | — | — | EP | disclosed |
| US-5336664-A | Compositions having herbicidal activity containing N-alkyl-amides as active ingredient | ZAMBON GROUP S.P.A. (IT) | 1994-08-09 | — | — | US | disclosed |
| EP-0454067-A1 | Compositions having herbicidal activity containing N-Alkyl-amides as active ingredient | ZAMBON GROUP S.p.A. (IT) | 1991-10-30 | — | — | EP | disclosed |