SCHEMBL168016

SCHEMBL168016

CCCCCC1=NCCN1

nearest known ligand 0.57

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
HTR1D P28221 4/20 0.57
NISCH Q9Y2I1 3/20 0.47
MAOA P21397 1/20 0.47
MAOB P27338 1/20 0.47
TAAR1 Q96RJ0 4/20 0.43
ADRA2B P18089 3/20 0.43
ADRA2C P18825 3/20 0.43
ADRA2A P08913 2/20 0.43
HTR1A P08908 1/20 0.43
HTR1B P28222 1/20 0.41
LMNA P02545 1/20 0.40
CYP1A2 P05177 1/20 0.40
CYP2D6 P10635 1/20 0.40
TSHR P16473 1/20 0.40
ADRA1D P25100 1/20 0.40
ADRA1A P35348 1/20 0.40
ADRA1B P35368 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7756299 0.98 HTR1D (0.56) HTR1DNISCHMAOAMAOBTAAR1
SCHEMBL1626311 0.98 HTR1D (0.56) HTR1DNISCHMAOAMAOBTAAR1
SCHEMBL15561019 0.98 HTR1D (0.56) HTR1DNISCHMAOAMAOBTAAR1
SCHEMBL5675527 0.98 HTR1D (0.56) HTR1DNISCHMAOAMAOBTAAR1
SCHEMBL107099 0.98 HTR1D (0.56) HTR1DNISCHMAOAMAOBTAAR1
SCHEMBL1736375 0.98 HTR1D (0.56) HTR1DNISCHMAOAMAOBTAAR1
SCHEMBL2845525 0.98 HTR1D (0.56) HTR1DNISCHMAOAMAOBTAAR1
SCHEMBL5680179 0.98 HTR1D (0.56) HTR1DNISCHMAOAMAOBTAAR1
Propane SCHEMBL9444503 0.98 HTR1D (0.56) HTR1DNISCHMAOAMAOBTAAR1
SCHEMBL10621181 0.98 HTR1D (0.56) HTR1DNISCHMAOAMAOBTAAR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 692 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117466818-B Method for preparing 2-aryl imidazoline compounds by solvent-free method 潍坊弘润新材料有限公司 2024-04-26 CN claimed
CN-117466818-A Method for preparing 2-aryl imidazoline compounds by solvent-free method 潍坊弘润新材料有限公司 2024-01-30 CN claimed
CN-210946251-U Antibacterial fabric 义乌市中力工贸有限公司 2020-07-07 CN claimed
CN-107419280-A A kind of stainless steel anti-corrosion passivation cream and preparation method thereof 苏州吉利不锈钢制品有限公司 2017-12-01 CN claimed
CN-106536697-A Fabric and home care treatment compositions 宝洁公司 2017-03-22 CN claimed
WO-1999052897-A1 NOVEL REAGENTS FOR USE AS COUPLING ACTIVATORS AND COUPLING REAGENTS IN ORGANIC SYNTHESIS NEXSTAR PHARMACEUTICALS, INC. (US) 1999-10-21 WO claimed
EP-0380019-B1 Methadone fluorescence polarization immunoassay ABBOTT LAB (US) 1995-11-08 EP claimed
US-12037641-B2 Modified nucleotide reagents PACIFIC BIOSCIENCES OF CALIFORNIA, INC. (US) 2024-07-16 US disclosed
CN-117701325-B Non-sulfur-chlorine system stainless steel cold rolling oil and preparation method and test method thereof 超滑科技(佛山)有限责任公司 2024-07-16 CN disclosed
US-12000000-B2 Labeled nucleotide analogs, reaction mixtures, and methods and systems for sequencing PACIFIC BIOSCIENCES OF CALIFORNIA, INC. (US) 2024-06-04 US disclosed
CN-113316585-B 3' -Protected nucleotides 豪夫迈·罗氏有限公司 2024-06-04 CN disclosed
US-20240158640-A1 PROTECTED DYE-LABELED REAGENTS PACIFIC BIOSCIENCES OF CALIFORNIA, INC. (US) 2024-05-16 US disclosed
CN-117466818-B Method for preparing 2-aryl imidazoline compounds by solvent-free method 潍坊弘润新材料有限公司 2024-04-26 CN disclosed
US-4230789-A SUBSTITUTED IMIDAZOLINE ACID NEUTRALIZERS MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1980-10-28 US disclosed
US-4223087-A TREATING SURFACE WITH SOLUTION OF A FERRICYANIDE ANION AND A COMPLEXING AGENT; OXIDATION MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1980-09-16 US disclosed
US-4219647-A Certain amides of prostacyclin and related compounds FRIED JOSEF 1980-08-26 US disclosed
US-4204868-A PHOTOLITHOGRAPHY OLEOPHILIC SILVER MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1980-05-27 US disclosed
US-4082735-A NOVEL IMMUNOLOGICAL ADJUVANT COMPOUNDS AND METHODS OF PREPARATION THEREOF SYNTEX (U.S.A.) INC. (US) 1978-04-04 US disclosed
US-4082736-A NOVEL IMMUNOLOGICAL ADJUVANT COMPOUNDS AND METHODS OF PREPARATION THEREOF SYNTEX (U.S.A.) INC. (US) 1978-04-04 US disclosed
US-4029702-A Oil-soluble bicarbamamide compounds ROHM AND HAAS COMPANY (US) 1977-06-14 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12037641-B2 Modified nucleotide reagents POLL, POLN, POLM HTR1D 3377/4885NISCH 612/4885MAOA 2805/4885
US-12000000-B2 Labeled nucleotide analogs, reaction mixtures, and methods and systems for sequencing POLL, POLN, POLB HTR1D 2944/4885NISCH 769/4885MAOA 2536/4885
US-20240158640-A1 PROTECTED DYE-LABELED REAGENTS POLL, POLB, POLM HTR1D 3296/4885NISCH 913/4885MAOA 2104/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.