Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC17A5 | Q9NRA2 | 1/20 | 0.54 |
| ▸ | MDM4 | O15151 | 3/20 | 0.51 |
| ▸ | TP53 | P04637 | 3/20 | 0.51 |
| ▸ | TLR2 | O60603 | 2/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.47 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.47 |
| ▸ | CASP3 | P42574 | 2/20 | 0.46 |
| ▸ | MDM2 | Q00987 | 6/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16801838 | 0.96 | SLC17A5 (0.55) | SLC17A5MDM4TP53TLR2KMT2A | |
| SCHEMBL10073558 | 0.91 | TLR2 (0.59) | SLC17A5MDM4TP53TLR2KMT2A | |
| SCHEMBL8111105 | 0.91 | TLR2 (0.59) | SLC17A5MDM4TP53TLR2KMT2A | |
| SCHEMBL20780206 | 0.89 | TLR2 (0.53) | SLC17A5MDM4TP53TLR2KMT2A | |
| SCHEMBL4719374 | 0.88 | TLR2 (0.56) | SLC17A5MDM4TP53TLR2CASP3 | |
| SCHEMBL6158264 | 0.88 | SLC17A5 (0.54) | SLC17A5MDM4TP53TLR2KMT2A | |
| SCHEMBL7763897 | 0.87 | TLR2 (0.55) | SLC17A5MDM4TP53TLR2HDAC1 | |
| SCHEMBL16801787 | 0.87 | SLC17A5 (0.53) | SLC17A5MDM4TP53TLR2CASP3 | |
| SCHEMBL25362302 | 0.85 | MDM2 (0.57) | MDM4TP53TLR2KMT2ACASP3 | |
| SCHEMBL4600023 | 0.85 | MDM2 (0.57) | MDM4TP53TLR2KMT2ACASP3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9056141-B2 | Thiol-ene click chemistry for drug conjugates | SYNCHEM, INC. (US) | 2015-06-16 | — | — | US | disclosed |