Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.66 |
| ▸ | BRD4 | O60885 | 1/20 | 0.66 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.66 |
| ▸ | POLB | P06746 | 1/20 | 0.66 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.66 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.54 |
| ▸ | NPC1 | O15118 | 1/20 | 0.54 |
| ▸ | RAB9A | P51151 | 1/20 | 0.54 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.52 |
| ▸ | CCR2 | P41597 | 4/20 | 0.52 |
| ▸ | ADRA1D | P25100 | 3/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.50 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.50 |
| ▸ | ATM | Q13315 | 1/20 | 0.50 |
| ▸ | DRD2 | P14416 | 1/20 | 0.50 |
| ▸ | HTR2A | P28223 | 1/20 | 0.50 |
| ▸ | HTR7 | P34969 | 1/20 | 0.50 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16801519 | 0.88 | KDM4E (0.70) | KDM4EBRD4ALDH1A1POLBCREBBP | |
| SCHEMBL18324709 | 0.88 | KDM4E (0.72) | KDM4EBRD4ALDH1A1POLBCREBBP | |
| SCHEMBL16801499 | 0.83 | KDM4E (0.73) | KDM4EBRD4ALDH1A1POLBCREBBP | |
| SCHEMBL18324984 | 0.82 | KDM4E (0.76) | KDM4EBRD4ALDH1A1POLBCREBBP | |
| SCHEMBL16801679 | 0.82 | KDM4E (0.71) | KDM4EBRD4ALDH1A1POLBCREBBP | |
| SCHEMBL16801844 | 0.82 | KDM4E (0.67) | KDM4EBRD4ALDH1A1POLBCREBBP | |
| SCHEMBL16801762 | 0.81 | KDM4E (0.63) | KDM4EBRD4ALDH1A1POLBCREBBP | |
| SCHEMBL16801982 | 0.81 | CHRM4 (0.63) | KDM4EBRD4ALDH1A1POLBCREBBP | |
| SCHEMBL16801578 | 0.81 | KDM4E (0.70) | KDM4EBRD4ALDH1A1POLBCREBBP | |
| SCHEMBL5705116 | 0.81 | KDM4E (0.78) | KDM4EBRD4ALDH1A1POLBCREBBP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2015082499-A2 | PHARMACEUTICAL COMPOUND | IOMET PHARMA LTD (GB) | 2015-06-11 | — | — | WO | disclosed |