Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM4 | P08173 | 1/20 | 0.63 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.63 |
| ▸ | BRD4 | O60885 | 1/20 | 0.63 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.63 |
| ▸ | POLB | P06746 | 1/20 | 0.63 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.63 |
| ▸ | CCR2 | P41597 | 15/20 | 0.53 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16801580 | 0.89 | CHRM4 (0.63) | CHRM4KDM4EBRD4ALDH1A1POLB | |
| SCHEMBL18324810 | 0.87 | CHRM4 (0.67) | CHRM4KDM4EBRD4ALDH1A1POLB | |
| SCHEMBL16802119 | 0.84 | KDM4E (0.71) | CHRM4KDM4EBRD4ALDH1A1POLB | |
| SCHEMBL16801948 | 0.84 | KDM4E (0.70) | CHRM4KDM4EBRD4ALDH1A1POLB | |
| SCHEMBL16801981 | 0.84 | KDM4E (0.64) | CHRM4KDM4EBRD4ALDH1A1POLB | |
| SCHEMBL16801774 | 0.81 | KDM4E (0.66) | CHRM4KDM4EBRD4ALDH1A1POLB | |
| SCHEMBL16801762 | 0.81 | KDM4E (0.63) | CHRM4KDM4EBRD4ALDH1A1POLB | |
| SCHEMBL13853726 | 0.79 | KDM4E (0.74) | CHRM4KDM4EBRD4ALDH1A1POLB | |
| SCHEMBL6705926 | 0.78 | CHRM4 (0.73) | CHRM4KDM4EBRD4ALDH1A1POLB | |
| SCHEMBL18324984 | 0.78 | KDM4E (0.76) | CHRM4KDM4EBRD4ALDH1A1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2015082499-A2 | PHARMACEUTICAL COMPOUND | IOMET PHARMA LTD (GB) | 2015-06-11 | — | — | WO | disclosed |