Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM2 | P08172 | 3/20 | 0.52 |
| ▸ | CHRM5 | P08912 | 3/20 | 0.52 |
| ▸ | CHRM1 | P11229 | 3/20 | 0.52 |
| ▸ | CHRM3 | P20309 | 3/20 | 0.52 |
| ▸ | LMNA | P02545 | 2/20 | 0.52 |
| ▸ | HTR2C | P28335 | 2/20 | 0.52 |
| ▸ | BLM | P54132 | 2/20 | 0.52 |
| ▸ | CHRM4 | P08173 | 2/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.52 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.52 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.52 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.52 |
| ▸ | MEN1 | O00255 | 1/20 | 0.52 |
| ▸ | POLB | P06746 | 1/20 | 0.52 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.52 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.52 |
| ▸ | HRH1 | P35367 | 1/20 | 0.52 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.52 |
| ▸ | SLC22A1 | O15245 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16765935 | 0.82 | KCNH2 (0.55) | CHRM2CHRM5CHRM1CHRM3LMNA | |
| SCHEMBL16789061 | 0.80 | KMT2A (0.58) | CHRM2CHRM5CHRM1CHRM3LMNA | |
| SCHEMBL10517086 | 0.79 | KCNH2 (0.61) | KCNH2OPRK1OPRM1CHRNA7 | |
| SCHEMBL10517083 | 0.79 | KCNH2 (0.61) | KCNH2OPRK1OPRM1CHRNA7 | |
| Hydrochloric Acid SCHEMBL9384270 | 0.78 | KCNH2 (0.60) | KCNH2OPRK1OPRM1CHRNA7 | |
| Hydrochloric Acid SCHEMBL9384273 | 0.78 | KCNH2 (0.60) | KCNH2OPRK1OPRM1CHRNA7 | |
| SCHEMBL3711940 | 0.72 | LMNA (0.76) | CHRM2CHRM5CHRM1CHRM3LMNA | |
| SCHEMBL23494941 | 0.71 | CHRM1 (0.77) | CHRM2CHRM5CHRM1CHRM3LMNA | |
| SCHEMBL23494946 | 0.71 | CHRM1 (0.77) | CHRM2CHRM5CHRM1CHRM3LMNA | |
| SCHEMBL23494940 | 0.71 | CHRM1 (0.77) | CHRM2CHRM5CHRM1CHRM3LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2015082616-A1 | HETEROARYL DERIVATIVES FOR THE TREATMENT OF RESPIRATORY DISEASES | CHIESI FARMACEUTICI S.P.A. (IT) | 2015-06-11 | — | — | WO | disclosed |