Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | JAK3 | P52333 | 20/20 | 0.81 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16764589 | 0.90 | JAK3 (1.00) | JAK3 | |
| SCHEMBL16764591 | 0.90 | JAK3 (1.00) | JAK3 | |
| SCHEMBL23221815 | 0.83 | JAK3 (0.84) | JAK3 | |
| SCHEMBL16802029 | 0.82 | JAK3 (0.69) | JAK3 | |
| SCHEMBL19595492 | 0.82 | JAK3 (0.75) | JAK3 | |
| SCHEMBL23221728 | 0.79 | JAK3 (0.70) | JAK3 | |
| SCHEMBL16764961 | 0.78 | JAK3 (1.00) | JAK3 | |
| SCHEMBL16764962 | 0.78 | JAK3 (1.00) | JAK3 | |
| SCHEMBL16764802 | 0.78 | JAK3 (1.00) | JAK3 | |
| SCHEMBL16764800 | 0.78 | JAK3 (1.00) | JAK3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2015083028-A1 | PYRROLO[2,3-D]PYRIMIDINYL, PYRROLO[2,3-B]PYRAZINYL AND PYRROLO[2,3-D]PYRIDINYL ACRYLAMIDES | PFIZER INC. (US) | 2015-06-11 | — | — | WO | disclosed |