Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | JAK3 | P52333 | 20/20 | 0.84 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16764776 | 0.91 | JAK3 (1.00) | JAK3 | |
| SCHEMBL16764774 | 0.91 | JAK3 (1.00) | JAK3 | |
| SCHEMBL16764901 | 0.87 | JAK3 (1.00) | JAK3 | |
| SCHEMBL19596073 | 0.86 | JAK3 (0.84) | JAK3 | |
| SCHEMBL23221978 | 0.85 | JAK3 (0.79) | JAK3 | |
| SCHEMBL16788546 | 0.84 | JAK3 (1.00) | JAK3 | |
| SCHEMBL16802254 | 0.83 | JAK3 (0.81) | JAK3 | |
| SCHEMBL18719376 | 0.83 | JAK3 (0.76) | JAK3 | |
| SCHEMBL16788535 | 0.81 | JAK3 (1.00) | JAK3 | |
| SCHEMBL16766003 | 0.80 | JAK3 (1.00) | JAK3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3318565-B1 | PYRROLO[2,3-D]PYRIMIDINYL, PYRROLO[2,3-B]PYRAZINYL AND PYRROLO[2,3-D]PYRIDINYL ACRYLAMIDES | PFIZER (US) | 2021-04-14 | — | — | EP | disclosed |