Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 9/20 | 0.58 |
| ▸ | HPGD | P15428 | 1/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.54 |
| ▸ | TP53 | P04637 | 2/20 | 0.54 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.54 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.54 |
| ▸ | THRB | P10828 | 4/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.42 |
| ▸ | ATM | Q13315 | 1/20 | 0.41 |
| ▸ | HCAR2 | Q8TDS4 | 3/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | ZDHHC20 | Q5W0Z9 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17712532 | 1.00 | TSHR (0.58) | TSHRHPGDALDH1A1TP53HIF1A | |
| SCHEMBL3041892 | 0.94 | TSHR (0.63) | TSHRHPGDALDH1A1TP53HIF1A | |
| SCHEMBL136294 | 0.91 | TSHR (0.71) | TSHRHPGDALDH1A1TP53HIF1A | |
| SCHEMBL970916 | 0.88 | TSHR (0.58) | TSHRHPGDALDH1A1TP53HIF1A | |
| SCHEMBL31186299 | 0.87 | TSHR (0.65) | TSHRHPGDALDH1A1TP53HIF1A | |
| SCHEMBL8458247 | 0.86 | TSHR (0.68) | TSHRHPGDALDH1A1TP53HIF1A | |
| SCHEMBL11430967 | 0.86 | TSHR (0.78) | TSHRHPGDALDH1A1TP53HIF1A | |
| SCHEMBL13111368 | 0.86 | TSHR (0.78) | TSHRHPGDALDH1A1TP53HIF1A | |
| SCHEMBL244622 | 0.86 | TSHR (0.78) | TSHRHPGDALDH1A1TP53HIF1A | |
| SCHEMBL34233 | 0.86 | TSHR (0.78) | TSHRHPGDALDH1A1TP53HIF1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9329479-B2 | Lithographic printing plate precusor | AGFA GRAPHICS NV (BE) | 2016-05-03 | — | — | US | disclosed |
| US-9329479-B2 | Lithographic printing plate precusor | AGFA GRAPHICS NV (BE) | 2016-05-03 | — | — | US | disclosed |
| US-20150168837-A1 | LITHOGRAPHIC PRINTING PLATE PRECUSOR | ECO3 BV (BE) | 2015-06-18 | — | — | US | disclosed |
| US-20150168837-A1 | LITHOGRAPHIC PRINTING PLATE PRECUSOR | ECO3 BV (BE) | 2015-06-18 | — | — | US | disclosed |