SCHEMBL8458247

SCHEMBL8458247

C=CC(=O)OCC[Si](OCCCC)(OCCCC)OCCCC

nearest known ligand 0.68

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
TSHR P16473 7/20 0.68
HPGD P15428 1/20 0.68
ALDH1A1 P00352 5/20 0.48
CYP3A4 P08684 2/20 0.48
ATM Q13315 1/20 0.47
TP53 P04637 3/20 0.44
HIF1A Q16665 3/20 0.44
HSD17B10 Q99714 1/20 0.44
HCAR2 Q8TDS4 3/20 0.42
THRB P10828 3/20 0.41
MAPT P10636 1/20 0.37
RAB9A P51151 1/20 0.37
NPSR1 Q6W5P4 1/20 0.37
MAPK1 P28482 1/20 0.37
SMN1; SMN2 Q16637 1/20 0.37
APP P05067 1/20 0.35
ZDHHC20 Q5W0Z9 1/20 0.35
ZDHHC2 Q9UIJ5 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL136294 0.92 TSHR (0.71) TSHRHPGDALDH1A1CYP3A4ATM
SCHEMBL8461591 0.90 TSHR (0.56) TSHRHPGDALDH1A1CYP3A4ATM
SCHEMBL28471216 0.89 TSHR (0.67) TSHRHPGDALDH1A1CYP3A4ATM
SCHEMBL31186299 0.88 TSHR (0.65) TSHRHPGDALDH1A1CYP3A4ATM
SCHEMBL17712532 0.86 TSHR (0.58) TSHRHPGDALDH1A1CYP3A4ATM
SCHEMBL16804267 0.86 TSHR (0.58) TSHRHPGDALDH1A1CYP3A4ATM
SCHEMBL11762892 0.85 TSHR (0.66) TSHRHPGDALDH1A1CYP3A4ATM
SCHEMBL28013523 0.85 TSHR (0.51) TSHRHPGDALDH1A1CYP3A4ATM
SCHEMBL5698978 0.85 TSHR (0.65) TSHRHPGDALDH1A1CYP3A4ATM
SCHEMBL270021 0.84 TSHR (0.53) TSHRHPGDALDH1A1CYP3A4ATM

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-108300385-B Adhesive sheet, display, and method for producing same 琳得科株式会社 2022-02-15 CN disclosed
EP-0604677-B1 Method of making coated shaped articles MITSUBISHI RAYON CO (JP) 1999-08-11 EP disclosed
US-5470616-A Coated shaped articles and method of making same MITSUBISHI RAYON CO., LTD. (JP) 1995-11-28 US disclosed
EP-0604677-A1 Coated shaped articles and method of making same MITSUBISHI RAYON CO., LTD. (JP) 1994-07-06 EP disclosed
US-4026826-A ALKOXYSILANES JAPAN ATOMIC ENERGY RESEARCH INSTITUTE (JA) 1977-05-31 US disclosed