Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SPHK1 | Q9NYA1 | 13/20 | 0.48 |
| ▸ | SPHK2 | Q9NRA0 | 7/20 | 0.42 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.39 |
| ▸ | RARB | P10826 | 2/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | CYP2C8 | P10632 | 1/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16807053 | 1.00 | SPHK1 (0.48) | SPHK1SPHK2FFAR4RARBCYP3A4 | |
| SCHEMBL16807060 | 1.00 | SPHK1 (0.48) | SPHK1SPHK2FFAR4RARBCYP3A4 | |
| SCHEMBL16807055 | 0.99 | SPHK1 (0.47) | SPHK1SPHK2FFAR4RARBCYP2C9 | |
| SCHEMBL16807068 | 0.97 | SPHK1 (0.47) | SPHK1SPHK2FFAR4RARBCYP2C9 | |
| SCHEMBL16807082 | 0.97 | SPHK1 (0.47) | SPHK1SPHK2FFAR4CYP3A4CYP2C8 | |
| SCHEMBL16774552 | 0.96 | SPHK1 (0.45) | SPHK1SPHK2FFAR4CYP2C9 | |
| SCHEMBL17070348 | 0.96 | SPHK1 (0.45) | SPHK1SPHK2FFAR4CYP2C9 | |
| SCHEMBL16807062 | 0.96 | SPHK1 (0.45) | SPHK1SPHK2FFAR4CYP2C9 | |
| SCHEMBL16807058 | 0.96 | SPHK1 (0.45) | SPHK1SPHK2FFAR4CYP2C9 | |
| SCHEMBL16807050 | 0.94 | SPHK1 (0.45) | SPHK1SPHK2FFAR4CYP2C9S1PR3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20150166890-A1 | LIQUID-CRYSTALLINE MEDIUM | MERCK PATENT GMBH (DE) | 2015-06-18 | — | — | US | disclosed |