Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SPHK1 | Q9NYA1 | 13/20 | 0.45 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.39 |
| ▸ | SPHK2 | Q9NRA0 | 7/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16807062 | 1.00 | SPHK1 (0.45) | SPHK1FFAR4CYP2C9ESR2SPHK2 | |
| SCHEMBL16774552 | 1.00 | SPHK1 (0.45) | SPHK1FFAR4CYP2C9ESR2SPHK2 | |
| SCHEMBL16807082 | 0.99 | SPHK1 (0.47) | SPHK1FFAR4CYP2C9ESR2SPHK2 | |
| SCHEMBL16807055 | 0.97 | SPHK1 (0.47) | SPHK1FFAR4CYP2C9ESR2SPHK2 | |
| SCHEMBL16807046 | 0.97 | SPHK1 (0.43) | SPHK1FFAR4CYP2C9ESR2SPHK2 | |
| SCHEMBL16807060 | 0.96 | SPHK1 (0.48) | SPHK1FFAR4CYP2C9SPHK2 | |
| SCHEMBL16807053 | 0.96 | SPHK1 (0.48) | SPHK1FFAR4CYP2C9SPHK2 | |
| SCHEMBL16807067 | 0.96 | SPHK1 (0.48) | SPHK1FFAR4CYP2C9SPHK2 | |
| SCHEMBL16807059 | 0.94 | SPHK1 (0.43) | SPHK1FFAR4CYP2C9ESR2SPHK2 | |
| SCHEMBL30967307 | 0.94 | SPHK1 (0.43) | SPHK1FFAR4CYP2C9ESR2SPHK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2918658-B1 | Liquid crystalline media with homeotropic alignment | MERCK PATENT GMBH (DE) | 2020-05-13 | — | — | EP | disclosed |
| EP-3323872-B1 | COMPOUNDS FOR HOMOTROPIC ALIGNMENT OF LIQUID CRYSTAL MEDIA | MERCK PATENT GMBH (DE) | 2020-04-15 | — | — | EP | disclosed |
| US-10513657-B2 | Liquid-crystalline media having homeotropic alignment | MERCK PATENT GMBH (DE) | 2019-12-24 | — | — | US | disclosed |
| US-10294426-B2 | Liquid crystalline media having homeotropic alignment | MERCK PATENT GMBH (DE) | 2019-05-21 | — | — | US | disclosed |
| US-20180208848-A1 | LIQUID CRYSTALLINE MEDIA HAVING HOMEOTROPIC ALIGNMENT | MERCK PATENT GMBH (DE) | 2018-07-26 | — | — | US | disclosed |
| US-20180208848-A1 | LIQUID CRYSTALLINE MEDIA HAVING HOMEOTROPIC ALIGNMENT | MERCK PATENT GMBH (DE) | 2018-07-26 | — | — | US | disclosed |
| US-20180142152-A1 | COMPOUNDS FOR THE HOMEOTROPIC ALIGNMENT OF LIQUID-CRYSTALLINE MEDIA | MERCK PATENT GMBH (DE) | 2018-05-24 | — | — | US | disclosed |
| US-20180142152-A1 | COMPOUNDS FOR THE HOMEOTROPIC ALIGNMENT OF LIQUID-CRYSTALLINE MEDIA | MERCK PATENT GMBH (DE) | 2018-05-24 | — | — | US | disclosed |
| US-20180057743-A1 | LIQUID-CRYSTALLINE MEDIA HAVING HOMEOTROPIC ALIGNMENT | MERCK PATENT GMBH (DE) | 2018-03-01 | — | — | US | disclosed |
| US-20180057743-A1 | LIQUID-CRYSTALLINE MEDIA HAVING HOMEOTROPIC ALIGNMENT | MERCK PATENT GMBH (DE) | 2018-03-01 | — | — | US | disclosed |
| US-9809748-B2 | Liquid-crystalline media having homeotropic alignment | MERCK PATENT GMBH (DE) | 2017-11-07 | — | — | US | disclosed |
| US-9809748-B2 | Liquid-crystalline media having homeotropic alignment | MERCK PATENT GMBH (DE) | 2017-11-07 | — | — | US | disclosed |
| WO-2017045740-A1 | LIQUID-CRYSTALLINE MEDIA HAVING HOMEOTROPIC ALIGNMENT | MERCK PATENT GMBH (DE) | 2017-03-23 | — | — | WO | disclosed |
| WO-2016015803-A1 | LIQUID CRYSTALLINE MEDIA HAVING HOMEOTROPIC ALIGNMENT | MERCK PATENT GMBH (DE) | 2016-02-04 | — | — | WO | disclosed |
| EP-2918658-A2 | Liquid crystalline media with homeotropic alignment | Merck Patent GmbH (DE) | 2015-09-16 | — | — | EP | disclosed |
| US-20150252265-A1 | LIQUID-CRYSTALLINE MEDIA HAVING HOMEOTROPIC ALIGNMENT | MERCK PATENT GMBH (DE) | 2015-09-10 | — | — | US | disclosed |
| US-20150252265-A1 | LIQUID-CRYSTALLINE MEDIA HAVING HOMEOTROPIC ALIGNMENT | MERCK PATENT GMBH (DE) | 2015-09-10 | — | — | US | disclosed |