Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | XIAP | P98170 | 20/20 | 0.62 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16780528 | 1.00 | XIAP (0.62) | XIAP | |
| SCHEMBL16780531 | 1.00 | XIAP (0.62) | XIAP | |
| SCHEMBL16807554 | 0.95 | XIAP (0.61) | XIAP | |
| SCHEMBL16810116 | 0.95 | XIAP (0.61) | XIAP | |
| SCHEMBL17758138 | 0.95 | XIAP (0.61) | XIAP | |
| SCHEMBL16807557 | 0.95 | XIAP (0.61) | XIAP | |
| SCHEMBL17758139 | 0.95 | XIAP (0.61) | XIAP | |
| SCHEMBL15424984 | 0.95 | XIAP (0.61) | XIAP | |
| SCHEMBL18034818 | 0.95 | XIAP (0.61) | XIAP | |
| SCHEMBL16780579 | 0.92 | XIAP (0.64) | XIAP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9345740-B2 | IAP antagonists | BRISTOL-MYERS SQUIBB COMPANY (US) | 2016-05-24 | — | — | US | disclosed |
| US-20150164974-A1 | IAP ANTAGONISTS | BRISTOL-MYERS SQUIBB COMPANY | 2015-06-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150164974-A1 | IAP ANTAGONISTS | XIAP, BIRC5, API5 | XIAP 1/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.