SCHEMBL16808239

SCHEMBL16808239

CC(C)(C)[Si](C)(C)OCCCCOc1ccc(C#N)cc1Br

nearest known ligand 0.38

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
AR P10275 1/20 0.38
CYP1A2 P05177 1/20 0.35
CYP2D6 P10635 1/20 0.35
CYP2C19 P33261 1/20 0.35
L3MBTL1 Q9Y468 4/20 0.35
MAPT P10636 3/20 0.35
HPGD P15428 3/20 0.35
LMNA P02545 1/20 0.35
MAPK1 P28482 1/20 0.35
NR3C1 P04150 4/20 0.35
FFAR1 O14842 1/20 0.34
TDP1 Q9NUW8 3/20 0.34
ALDH1A1 P00352 2/20 0.34
NPC1 O15118 1/20 0.34
RAB9A P51151 1/20 0.34
SMN1; SMN2 Q16637 1/20 0.34
KDM4E B2RXH2 1/20 0.34
DUT P33316 1/20 0.34
ICMT O60725 1/20 0.34
TRPV4 Q9HBA0 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16808234 0.86 MRGPRX4 (0.44) ARMAPTRAB9AKDM4EDUT
SCHEMBL16808273 0.85 ICMT (0.47) ARL3MBTL1MAPTHPGDLMNA
SCHEMBL16808224 0.85 ICMT (0.45) ARNR3C1SMN1; SMN2KDM4EICMT
SCHEMBL16808295 0.85 HRH3 (0.39) ARNR3C1DUTICMTTRPV4
SCHEMBL27938601 0.79 HPGD (0.48) CYP1A2CYP2D6CYP2C19L3MBTL1MAPT
SCHEMBL10051529 0.79 AR (0.40) ARCYP1A2CYP2D6CYP2C19L3MBTL1
SCHEMBL23132941 0.78 ICMT (0.36) MAPTALDH1A1NPC1RAB9ASMN1; SMN2
SCHEMBL19032942 0.78 ICMT (0.46) ARMAPTICMTTRPV4PLAU
SCHEMBL406833 0.78 AR (0.39) ARNR3C1ICMTTRPV4
SCHEMBL6246819 0.78 F2 (0.43) ARCYP1A2CYP2D6CYP2C19L3MBTL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2015087857-A1 ARYL AMIDINE COMPOUND AND BACTERICIDAL AGENT 日本曹達株式会社 2015-06-18 WO disclosed