SCHEMBL168085

SCHEMBL168085

C=CC[Si](Cl)(CC=C)CC=C

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5497835 0.83
SCHEMBL2167757 0.81
SCHEMBL15302844 0.81 TSHR (0.32)
SCHEMBL27574 0.77
SCHEMBL231601 0.77
SCHEMBL6063988 0.76 TSHR (0.35)
SCHEMBL15302560 0.76 TSHR (0.35)
SCHEMBL1493194 0.74
SCHEMBL6064250 0.73 TSHR (0.40)
SCHEMBL15301912 0.73 TSHR (0.40)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1608 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240170228-A1 IONIC PLASTIC CRYSTALS, COMPOSITIONS COMPRISING SAME, METHODS FOR MANUFACTURING SAME AND USES THEREOF HYDRO-QUéBEC (CA) 2024-05-23 US claimed
EP-4288439-A1 IONIC PLASTIC CRYSTALS, COMPOSITIONS COMPRISING SAME, METHODS FOR MANUFACTURING SAME AND USES THEREOF Hydro-Québec (CA) 2023-12-13 EP claimed
CN-116806221-A Ionic plastic crystals, compositions comprising the same, methods of manufacture and uses thereof 魁北克电力公司 2023-09-26 CN claimed
CN-116239804-A Long-chain branched high-density polyethylene and preparation method thereof 中国石油天然气股份有限公司 2023-06-09 CN claimed
CN-111892778-B Impact-resistant co-polypropylene and polypropylene composition and respective preparation method 中国石油化工股份有限公司 2022-12-27 CN claimed
CN-113816978-A Diamine-boronic ester complex and preparation method and application thereof 北京大学 2021-12-21 CN claimed
CN-112851892-A Preparation method of polypropylene with high melt strength 中国石油天然气股份有限公司 2021-05-28 CN claimed
EP-3363825-B1 USE OF ORGANIC SILOXANE, AND POLYOLEFIN IN-REACTOR ALLOY AND PREPARATION METHOD THEREOF INST CHEMISTRY CAS (CN) 2021-04-14 EP claimed
CN-111892778-A Impact-resistant co-polypropylene and polypropylene composition and respective preparation method 中国石油化工股份有限公司 2020-11-06 CN claimed
US-10717801-B2 Use of organosilane, in-reactor polyolefin alloy and preparation method thereof INSTITUTE OF CHEMISTRY, CHINESE ACADEMY OF SCIENCES (CN) 2020-07-21 US claimed
WO-1993023413-A1 SYNTHESIS OF NUCLEOTIDE MONOMERS RIBOZYME PHARMACEUTICALS, INC. (US) 1993-11-25 WO claimed
WO-1993015103-A2 NOVEL STEROID INTERMEDIATES AND PROCESSES FOR THEIR PREPARATION SCHERING CORPORATION (US) 1993-08-05 WO claimed
US-5112996-A METHOD FOR ALKYLATING GUANIDINO GROUPS SCLAVO S.P.A. (IT) 1992-05-12 US claimed
US-5071966-A PROCESS FOR PREPARING AN ENOL SILYL ETHER COMPOUND KANEGAFUCHI KAGAKU KOGYO KABUSHIKI KAISHA (JP) 1991-12-10 US claimed
US-5008471-A Process for the preparation of rooperol ROOPEROL (N.A.) (NL) 1991-04-16 US claimed
EP-0416417-A2 New method for alkylating guanidino groups SCLAVO S.p.A. (IT) 1991-03-13 EP claimed
EP-0414904-A1 PREPARATION OF ENOL SILYL ETHER COMPOUNDS KANEGAFUCHI KAGAKU KOGYO KABUSHIKI KAISHA (JP) 1991-03-06 EP claimed
US-4956502-A Process for the preparation of rooperol derivative ROOPEROL (N.A.) NV (AN) 1990-09-11 US claimed
EP-0361827-A1 Pyrazole compounds, method for production thereof, use thereof and intermediates for production thereof SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1990-04-04 EP claimed
EP-0206765-A2 Process for preparation of rooperol, hypoxoside and derivatives thereof ROOPEROL (NA) NV (NL) 1986-12-30 EP claimed