⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL168085 | 0.83 | — | — | |
| SCHEMBL2167757 | 0.73 | — | — | |
| SCHEMBL15302844 | 0.73 | TSHR (0.32) | — | |
| SCHEMBL253633 | 0.71 | — | — | |
| SCHEMBL6046412 | 0.71 | — | — | |
| SCHEMBL231601 | 0.69 | — | — | |
| SCHEMBL27574 | 0.69 | — | — | |
| SCHEMBL6063988 | 0.69 | TSHR (0.35) | — | |
| SCHEMBL15302560 | 0.69 | TSHR (0.35) | — | |
| SCHEMBL1493194 | 0.67 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7297343-B2 | Bioactive medical films | BIOSURFACE ENGINEERING TECHNOLOGIES, INC. (US) | 2007-11-20 | — | — | US | disclosed |
| EP-1311551-A4 | BIOACTIVE COATING COMPOSITIONS AND METHODS | BIOSURFACE ENG TECH INC (US) | 2007-04-18 | — | — | EP | disclosed |
| US-6921811-B2 | Bioactive coating composition and methods | BIOSURFACE ENGINEERING TECHNOLOGIES, INC. (US) | 2005-07-26 | — | — | US | disclosed |
| US-20040161442-A1 | Bioactive coating composition and methods | BIOSURFACE ENGINEERING TECHNOLOGIES, INC. | 2004-08-19 | — | — | US | disclosed |
| US-20040151764-A1 | Bioactive medical films | BIOSURFACE ENGINEERING TECHNOLOGIES, INC. (US) | 2004-08-05 | — | — | US | disclosed |
| EP-1159302-B1 | NON-THROMBOGENIC SILYL MODIFIED HEPARIN COATING COMPOSITION AND METHODS FOR USING SAME | INNERDYNE MEDICAL INC (US) | 2004-03-31 | — | — | EP | disclosed |
| US-6630580-B2 | Silyl heparin complex for use in attaching cells to prostheses, including vascular grafts and bone grafts | INNERDYNE, INC. | 2003-10-07 | — | — | US | disclosed |
| US-6596699-B2 | Polyanion substrate having bound thereto by non-covalent means a condensate comprising a polycation and nucleic acid; for contacting surfaces of medical devices | BIOSURFACE ENGINEERING TECHNOLOGIES, INC. | 2003-07-22 | — | — | US | disclosed |
| EP-1311551-A1 | BIOACTIVE COATING COMPOSITIONS AND METHODS | Biosurface Engineering Technologies, Inc. (US) | 2003-05-21 | — | — | EP | disclosed |
| US-20020160098-A1 | Nucleic acid coating compositions and methods | BIOSURFACE ENGINEERING TECHNOLOGIES, INC. | 2002-10-31 | — | — | US | disclosed |
| US-20020115836-A1 | Non-thrombogenic coating composition and methods for using same | BIOSURFACE ENGINEERING TECHNOLOGIES, INC. | 2002-08-22 | — | — | US | disclosed |
| WO-2002010221-A1 | BIOACTIVE COATING COMPOSITIONS AND METHODS | BIOSURFACE ENGINEERING TECHNOLOGIES, INC. (US) | 2002-02-07 | — | — | WO | disclosed |
| US-6342591-B1 | Amphipathic coating for modulating cellular adhesion composition and methods | BIOSURFACE ENGINEERING TECHNOLOGIES, INC. | 2002-01-29 | — | — | US | disclosed |
| US-5955588-A | COVALENT COMPLEX OF 1 TO 30 HYDROPHOBIC SILYL MOIETIES DIRECTLY BOUND TO SODIUM HEPARIN VIA COVALENT BONDING; STABLE ANTICOAGULANT ACTIVITY OVER TIME; COST-EFFECTIVE PRODUCTION; FOR USE IN MEDICAL DEVICES | INNERDYNE, INC. (US) | 1999-09-21 | — | — | US | disclosed |
| US-4496551-A | Fungicidal imidazole derivatives | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1985-01-29 | — | — | US | disclosed |