Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.52 |
| ▸ | LMNA | P02545 | 1/20 | 0.52 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
| ▸ | HPGD | P15428 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.49 |
| ▸ | ACHE | P22303 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.48 |
| ▸ | MAPT | P10636 | 2/20 | 0.48 |
| ▸ | ACP3 | P15309 | 1/20 | 0.48 |
| ▸ | GRM8 | O00222 | 4/20 | 0.47 |
| ▸ | GRM4 | Q14833 | 4/20 | 0.47 |
| ▸ | GRM6 | O15303 | 3/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.44 |
| ▸ | KMO | O15229 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4703596 | 0.85 | TSHR (0.53) | TSHRLMNAL3MBTL1MEN1HPGD | |
| SCHEMBL16805953 | 0.84 | KMT2A (0.51) | TSHRLMNAL3MBTL1MEN1HPGD | |
| SCHEMBL666103 | 0.83 | GRM8 (0.53) | TSHRLMNAL3MBTL1MEN1HPGD | |
| SCHEMBL31226322 | 0.83 | GRM8 (0.53) | TSHRLMNAL3MBTL1MEN1HPGD | |
| SCHEMBL666980 | 0.83 | CYP2D6 (0.48) | TSHRLMNAL3MBTL1MEN1HPGD | |
| SCHEMBL31226485 | 0.83 | CYP2D6 (0.48) | TSHRLMNAL3MBTL1MEN1HPGD | |
| SCHEMBL9298304 | 0.83 | KMT2A (0.53) | TSHRLMNAL3MBTL1MEN1HPGD | |
| SCHEMBL666474 | 0.81 | GRM8 (0.49) | TSHRLMNAL3MBTL1MEN1HPGD | |
| SCHEMBL10609292 | 0.81 | TSHR (0.53) | TSHRLMNAL3MBTL1MEN1HPGD | |
| SCHEMBL18896279 | 0.81 | KMT2A (0.58) | TSHRLMNAL3MBTL1MEN1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116023283-A | Preparation method of m-nitro aromatic ring compound | 上海创拓生物科技有限公司 | 2023-04-28 | — | — | CN | claimed |
| CN-116023283-B | Preparation method of m-nitro aromatic ring compound | 上海创拓生物科技有限公司 | 2025-05-23 | — | — | CN | disclosed |
| US-20230192644-A1 | PIPERIDINE-2,6-DIONES AS SMALL MOLECULE DEGRADERS OF HELIOS AND METHODS OF USE | DANA-FARBER CANCER INSTITUTE, INC. (US) | 2023-06-22 | — | — | US | disclosed |
| US-20230192644-A1 | PIPERIDINE-2,6-DIONES AS SMALL MOLECULE DEGRADERS OF HELIOS AND METHODS OF USE | DANA-FARBER CANCER INSTITUTE, INC. (US) | 2023-06-22 | — | — | US | disclosed |
| CN-116023283-A | Preparation method of m-nitro aromatic ring compound | 上海创拓生物科技有限公司 | 2023-04-28 | — | — | CN | disclosed |
| CN-116023283-A | Preparation method of m-nitro aromatic ring compound | 上海创拓生物科技有限公司 | 2023-04-28 | — | — | CN | disclosed |
| EP-4153175-A1 | PIPERIDINE-2,6-DIONES AS SMALL MOLECULE DEGRADERS OF HELIOS AND METHODS OF USE | Dana-Farber Cancer Institute, Inc. (US) | 2023-03-29 | — | — | EP | disclosed |
| US-9481684-B2 | Gonadotropin releasing hormone receptor antagonists, method for the preparation thereof and pharmaceutical composition comprising the same | SK CHEMICALS CO., LTD. (KR) | 2016-11-01 | — | — | US | disclosed |
| US-20150166558-A1 | GONADOTROPIN RELEASING HORMONE RECEPTOR ANTAGONISTS, METHOD FOR THE PREPARATION THEREOF AND PHARMACEUTICAL COMPOSITION COMPRISING THE SAME | SK CHEMICALS CO., LTD. (KR) | 2015-06-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150166558-A1 | GONADOTROPIN RELEASING HORMONE RECEPTOR ANTAGONISTS, METHOD FOR THE PREPARATION THEREOF AND PHARMACEUTICAL COMPOSITION COMPRISING THE SAME | GNRHR, FSHR, GHRHR | TSHR 50/4885LMNA 417/4885L3MBTL1 4743/4885 |
| US-20230192644-A1 | PIPERIDINE-2,6-DIONES AS SMALL MOLECULE DEGRADERS OF HELIOS AND METHODS OF USE | IKZF2, IKZF1, NUTF2 | TSHR 4330/4885LMNA 1156/4885L3MBTL1 3511/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.