Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 8/20 | 0.35 |
| ▸ | TSHR | P16473 | 2/20 | 0.35 |
| ▸ | VCP | P55072 | 1/20 | 0.34 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.34 |
| ▸ | CHRM2 | P08172 | 4/20 | 0.32 |
| ▸ | CHRM1 | P11229 | 4/20 | 0.32 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
| ▸ | MBTD1 | Q05BQ5 | 1/20 | 0.32 |
| ▸ | L3MBTL3 | Q96JM7 | 1/20 | 0.32 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10092700 | 0.81 | HRH3 (0.41) | HRH3TSHRVCPCHRM2CHRM1 | |
| SCHEMBL18372271 | 0.81 | HRH3 (0.38) | HRH3TSHRCHRNA7CHRM2CHRM1 | |
| SCHEMBL14453902 | 0.79 | HRH3 (0.41) | HRH3TSHRVCPTP53MBTD1 | |
| SCHEMBL23384260 | 0.77 | HRH3 (0.40) | HRH3TSHRVCPTP53MBTD1 | |
| SCHEMBL10092689 | 0.77 | HRH3 (0.50) | HRH3TSHRCHRM2CHRM1TP53 | |
| SCHEMBL12396793 | 0.77 | HRH3 (0.46) | HRH3TSHRCHRM2CHRM1TP53 | |
| SCHEMBL8186259 | 0.75 | HRH3 (0.53) | HRH3TSHRCHRM2CHRM1TP53 | |
| SCHEMBL12858869 | 0.75 | HRH3 (0.53) | HRH3TSHRCHRM2CHRM1TP53 | |
| SCHEMBL22456342 | 0.74 | HRH3 (0.41) | HRH3TSHRVCPTP53MBTD1 | |
| SCHEMBL14191716 | 0.74 | L3MBTL3 (0.45) | MBTD1L3MBTL3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2015088045-A1 | PYRROLO[3,2-C]PYRIDINE DERIVATIVES AS TLR INHIBITORS | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2015-06-18 | — | — | WO | disclosed |