⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12600025 | 0.82 | — | — | |
| SCHEMBL25741898 | 0.82 | — | — | |
| SCHEMBL17640961 | 0.82 | — | — | |
| SCHEMBL12927034 | 0.82 | — | — | |
| SCHEMBL9727023 | 0.82 | — | — | |
| SCHEMBL24079390 | 0.82 | — | — | |
| SCHEMBL15133755 | 0.78 | INPP5A (0.30) | — | |
| SCHEMBL17772385 | 0.78 | — | — | |
| SCHEMBL25922017 | 0.76 | — | — | |
| SCHEMBL16411427 | 0.75 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2015089462-A1 | DELIVERY, USE AND THERAPEUTIC APPLICATIONS OF THE CRISPR-CAS SYSTEMS AND COMPOSITIONS FOR GENOME EDITING | The Broad Institute Inc. (US) | 2015-06-18 | — | — | WO | disclosed |