⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19591091 | 0.88 | SMPD1 (0.44) | — | |
| SCHEMBL24754053 | 0.84 | SMPD1 (0.53) | — | |
| SCHEMBL19478198 | 0.82 | — | — | |
| SCHEMBL10051597 | 0.78 | — | — | |
| SCHEMBL2628202 | 0.76 | — | — | |
| SCHEMBL22280504 | 0.75 | GBA1 (0.43) | — | |
| SCHEMBL19368290 | 0.75 | — | — | |
| SCHEMBL21524622 | 0.74 | — | — | |
| SCHEMBL1753962 | 0.74 | GBA1 (0.45) | — | |
| SCHEMBL19830216 | 0.74 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20200181256-A1 | ANTI SEZ6 ANTIBODIES AND METHODS OF USE | ABBVIE STEMCENTRX LLC (US) | 2020-06-11 | — | — | US | disclosed |
| WO-2015088885-A1 | SOLUBLE GUANYLATE CYCLASE ACTIVATORS | MERCK SHARP & DOHME CORP. (US) | 2015-06-18 | — | — | WO | disclosed |