SCHEMBL16821

SCHEMBL16821

CC(=O)C(F)(F)F

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16370918 1.00 LMNA (0.42)
SCHEMBL18906335 1.00
Methyl Alcohol SCHEMBL28633344 0.96
Water SCHEMBL29184009 0.96 LMNA (0.39)
SCHEMBL11799633 0.96
Fluoride SCHEMBL28750147 0.96
Water SCHEMBL542920 0.96
Acetic Acid SCHEMBL31314449 0.92 FFAR3 (0.54)
SCHEMBL28791559 0.92 LMNA (0.36)
Hydrochloric Acid SCHEMBL9811400 0.92

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 5774 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4747333-A1 COMPOSITIONS COMPRISING 1,1,1,4,4,4-HEXAFLUORO-2-BUTYNE The Chemours Company FC, LLC (US) 2026-05-27 EP claimed
EP-4747220-A1 SYSTEMS AND PROCESSES FOR THE PRODUCTION OF Z-1,1,1,4,4,4-HEXAFLUORO-2-BUTENE The Chemours Company FC, LLC (US) 2026-05-27 EP claimed
CN-120272187-B High-temperature-resistant organic fluorescent powder and preparation method thereof 南京鸿辰中子科技有限公司 2026-05-22 CN claimed
WO-2026106065-A1 ANION EXCHANGE MEMBRANE WITH EXCELLENT PHASE SEPARATION PROPERTIES, ION CONDUCTIVITY, AND ALKALINE DURABILITY USING RADIAL POLYMER, METHOD FOR MANUFACTURING SAME, AND MEMBRANE ELECTRODE ASSEMBLY FOR WATER ELECTROLYSIS COMPRISING SAME 도레이첨단소재 주식회사 2026-05-21 WO claimed
CN-122059815-A Hexafluoroacetylacetone efficient synthesis method of (2) 济南万兴达化工有限公司 2026-05-19 CN claimed
CN-122010876-A 2-Methyl-5-trifluoromethyl furan and preparation method thereof 淄博飞源化工有限公司 2026-05-12 CN claimed
EP-4737533-A1 METHOD FOR SUPPRESSING DISPROPORTIONATION REACTION OF WORKING MEDIUM FOR REFRIGERATION CYCLES, WORKING MEDIUM FOR REFRIGERATION CYCLES, AND REFRIGERATION CYCLE DEVICE Panasonic Intellectual Property Management Co., Ltd. (JP) 2026-05-06 EP claimed
US-12617889-B1 Polymers for use as anion exchange membranes ENVISION ENERGY USA LTD. (US) 2026-05-05 US claimed
US-20260098197-A1 METHOD OF INHIBITING DISPROPORTIONATION REACTION OF REFRIGERATION-CYCLE WORKING FLUID, REFRIGERATION-CYCLE WORKING FLUID, AND REFRIGERATION CYCLE APPARATUS PANASONIC INTELLECTUAL PROPERTY MANAGEMENT CO., LTD. (JP) 2026-04-09 US claimed
US-20260022366-A1 ENGINEERED NITROALDOLASES CODEXIS INC (US) 2026-01-22 US claimed
US-4370244-A Process for cold mechanical working of metallic materials AKADEMIE DER WISSENSCHAFTEN DER DDR (DD) 1983-01-25 US claimed
US-4267333-A Preparation of 2-trifluoromethyl cinchoninic acids UNION CARBIDE AGRICULTURAL PRODUCTS COMPANY, INC. (US) 1981-05-12 US claimed
US-4263288-A Acaricidal, insecticidal, and nematocidal phosphoramidothioates ROHM AND HAAS COMPANY (US) 1981-04-21 US claimed
EP-0026894-A1 Process for the preparation of erythro-alpha-2-piperidyl-2,8-bis (trifluoromethyl)-4-quinoline methanol BASF Aktiengesellschaft (DE) 1981-04-15 EP claimed
US-4251661-A Preparation of 2-trifluoromethyl cinchoninic acids UNION CARBIDE CORPORATION (US) 1981-02-17 US claimed
US-4247359-A Preparation of epitaxial rare earth thin films HONEYWELL INC. (US) 1981-01-27 US claimed
US-4215009-A COMPLEXING ORONZIO DENORA IMPIANTI ELETTROCHIMICI S.P.A. (IT) 1980-07-29 US claimed
EP-0005859-A1 Process for reducing metal ion content of aqueous solutions DE NORA PERMELEC S.P.A. (IT) 1979-12-12 EP claimed
US-4149010-A Synthesis of α-trifluoromethyl vinyl acetate POLAROID CORPORATION (US) 1979-04-10 US claimed
EP-0001019-A1 Phenylhydrazones, their use in insecticidal compositions and methods for their preparation COMMONWEALTH SCIENTIFIC AND INDUSTRIAL RESEARCH ORGANISATION (AU) 1979-03-07 EP claimed