SCHEMBL1682125

SCHEMBL1682125

C=CC(=O)OC[SiH](C)C

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16853090 0.84
SCHEMBL28624266 0.80 TSHR (0.45)
SCHEMBL27901684 0.80 HCAR2 (0.44)
SCHEMBL28035756 0.77 TSHR (0.50)
SCHEMBL2584600 0.77 TSHR (0.47)
Acrylic Acid Ethyl Ester SCHEMBL28988595 0.76 TSHR (0.54)
SCHEMBL7641628 0.76
SCHEMBL28000540 0.76 TSHR (0.46)
SCHEMBL14119756 0.76 TSHR (0.44)
SCHEMBL1585542 0.74 TSHR (0.63)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-102666665-B Silicone compositions comprising a swollen silicone gel DOW CORNING 2015-07-22 CN claimed
CN-102666665-B Silicone compositions comprising a swollen silicone gel DOW CORNING 2015-07-22 CN disclosed
EP-2536786-A1 SURFACE -MODIFIED HYDROGELS AND HYDROGEL MICROPARTICLES Dow Corning Corporation (US) 2012-12-26 EP disclosed
EP-2536766-A1 SILOXANE SURFACE-MODIFIED HYDROGEL AND HYDROGEL MICROPARTICLE COMPOSITIONS Dow Corning Corporation (US) 2012-12-26 EP disclosed
EP-2490663-A2 SILICONE COMPOSITIONS COMPRISING A SWOLLEN SILICONE GEL Dow Corning Corporation (US) 2012-08-29 EP disclosed
WO-2011109174-A1 SURFACE -MODIFIED HYDROGELS AND HYDROGEL MICROPARTICLES DOW CORNING CORPORATION (US) 2011-09-09 WO disclosed
WO-2011103291-A1 SILOXANE SURFACE-MODIFIED HYDROGEL AND HYDROGEL MICROPARTICLE COMPOSITIONS DOW CORNING CORPORATION (US) 2011-08-25 WO disclosed
WO-2011049896-A2 SILICONE COMPOSITIONS COMPRISING A SWOLLEN SILICONE GEL DOW CORNING CORPORATION (US) 2011-04-28 WO disclosed
EP-2212457-A1 ARTICLE AND METHOD OF MANUFACTURING SAME Dow Corning Corporation (US) 2010-08-04 EP disclosed
WO-2009067230-A1 ARTICLE AND METHOD OF MANUFACTURING SAME DOW CORNING CORPORATION (US) 2009-05-28 WO disclosed
EP-1833864-A1 SILOXANES AND SILANES CURED BY ORGANOBORANE AMINE COMPLEXES Dow Corning Corporation (US) 2007-09-19 EP disclosed
EP-1805256-A1 CONDUCTIVE CURABLE COMPOSITIONS Dow Corning Corporation (US) 2007-07-11 EP disclosed
WO-2006073696-A1 SILOXANES AND SILANES CURED BY ORGANOBORANE AMINE COMPLEXES DOW CORNING CORPORATION (US) 2006-07-13 WO disclosed
WO-2006049792-A1 CONDUCTIVE CURABLE COMPOSITIONS DOW CORNING CORPORATION (US) 2006-05-11 WO disclosed
US-4910232-A Ultraviolet-curable organopolysiloxane composition SHIN-ETSU CHEMICAL CO., LTD. (JP) 1990-03-20 US disclosed