Levulinic Acid

Levulinic Acid

SCHEMBL1682244

CC(=O)CCC(=O)O.CC(C)O.CC(C)O.N

nearest known ligand 0.74

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LMNA P02545 3/20 0.74
SLC15A2 Q16348 1/20 0.74
ALDH1A1 P00352 2/20 0.53
EGLN1 Q9GZT9 4/20 0.48
KDM2A Q9Y2K7 4/20 0.48
KDM4E B2RXH2 2/20 0.48
KDM5C P41229 2/20 0.48
PHF8 Q9UPP1 2/20 0.48
KDM6B O15054 1/20 0.48
ALKBH5 Q6P6C2 1/20 0.47
SUCNR1 Q9BXA5 1/20 0.47
GABRP O00591 2/20 0.42
GABRD O14764 2/20 0.42
GABRA1 P14867 2/20 0.42
GABRB1 P18505 2/20 0.42
GABRG2 P18507 2/20 0.42
GABRB3 P28472 2/20 0.42
GABRA5 P31644 2/20 0.42
GABRA3 P34903 2/20 0.42
GABRA2 P47869 2/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Levulinic Acid SCHEMBL1682240 1.00 LMNA (0.74) LMNASLC15A2ALDH1A1EGLN1KDM2A
Levulinic Acid SCHEMBL28008923 0.97 LMNA (0.78) LMNASLC15A2ALDH1A1EGLN1KDM2A
Levulinic Acid SCHEMBL1682246 0.97 LMNA (0.78) LMNASLC15A2ALDH1A1EGLN1KDM2A
Levulinic Acid SCHEMBL183614 0.89
Levulinic Acid SCHEMBL28010828 0.87 LMNA (0.70) LMNASLC15A2ALDH1A1EGLN1KDM2A
Levulinic Acid SCHEMBL30530258 0.86
Levulinic Acid SCHEMBL113572 0.86 LMNA (1.00) LMNASLC15A2ALDH1A1EGLN1KDM2A
Succinic Acid SCHEMBL21081056 0.86 LMNA (0.64) LMNASLC15A2EGLN1KDM2AKDM4E
Levulinic Acid SCHEMBL27931545 0.86 LMNA (1.00) LMNASLC15A2ALDH1A1EGLN1KDM2A
Levulinic Acid SCHEMBL20868 0.86

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20160090600-A1 COMPOSITION FOR EXTERNAL APPLICATION COMPRISING TRANSCRIPTION FACTOR DECOY AS ACTIVE INGREDIENT ANGESMG, INC. (JP) 2016-03-31 US disclosed
EP-2266626-B1 COMPOSITION FOR EXTERNAL APPLICATION COMPRISING TRANSCRIPTION FACTOR DECOY AS ACTIVE INGREDIENT ANGESMG INC (JP) 2014-06-18 EP disclosed
US-20110092438-A1 Composition for external application comprising transcription factor decoy as active ingredient ANGESMG, INC. 2011-04-21 US disclosed
EP-2266626-A1 COMPOSITION FOR EXTERNAL APPLICATION COMPRISING TRANSCRIPTION FACTOR DECOY AS ACTIVE INGREDIENT AnGes MG, Inc. (JP) 2010-12-29 EP disclosed