Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2A | P28223 | 2/20 | 0.48 |
| ▸ | HTR2C | P28335 | 1/20 | 0.48 |
| ▸ | PKM | P14618 | 2/20 | 0.47 |
| ▸ | CHRM2 | P08172 | 2/20 | 0.46 |
| ▸ | CHRM3 | P20309 | 2/20 | 0.46 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 2/20 | 0.44 |
| ▸ | PGR | P06401 | 1/20 | 0.43 |
| ▸ | SCN1A | P35498 | 4/20 | 0.42 |
| ▸ | SCN8A | Q9UQD0 | 4/20 | 0.42 |
| ▸ | RORC | P51449 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | TRPV4 | Q9HBA0 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1682344 | 0.88 | CHRM2 (0.46) | CHRM2CHRM3OPRM1SCN1ASCN8A | |
| SCHEMBL1682352 | 0.87 | HTR2A (0.48) | HTR2AHTR2CCHRM2CHRM3OPRM1 | |
| SCHEMBL1682296 | 0.85 | HTR2A (0.53) | HTR2AHTR2CCHRM2CHRM3OPRM1 | |
| SCHEMBL1682312 | 0.83 | HTT (0.54) | PKMCHRM2CHRM3HTTSMN1; SMN2 | |
| SCHEMBL1682317 | 0.81 | CHRM4 (0.50) | HTR2AHTR2CCHRM2CHRM3OPRM1 | |
| SCHEMBL1682299 | 0.81 | KDM4E (0.49) | HTR2AHTR2CCHRM2CHRM3HTT | |
| SCHEMBL1682262 | 0.80 | CXCR4 (0.51) | OPRM1SMN1; SMN2 | |
| SCHEMBL1682268 | 0.80 | USP2 (0.55) | HTR2A | |
| SCHEMBL1682260 | 0.80 | CXCR4 (0.48) | HTR2AHTR2CCHRM2CHRM3OPRM1 | |
| SCHEMBL1682284 | 0.80 | CNR2 (0.52) | HTR2AHTR2CCHRM2CHRM3OPRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011043519-A2 | SULFONAMIDE DERIVATIVES AS SEROTONIN RECEPTOR ANTAGONIST AND SEROTONIN REUPTAKE INHIBITOR | KOREA INSTITUTE OF SCIENCE AND TECHNOLOGY (KR) | 2011-04-14 | — | — | WO | claimed |
| WO-2011043519-A2 | SULFONAMIDE DERIVATIVES AS SEROTONIN RECEPTOR ANTAGONIST AND SEROTONIN REUPTAKE INHIBITOR | KOREA INSTITUTE OF SCIENCE AND TECHNOLOGY (KR) | 2011-04-14 | — | — | WO | disclosed |