Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM2 | P08172 | 1/20 | 0.46 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.46 |
| ▸ | KCNA5 | P22460 | 1/20 | 0.46 |
| ▸ | SCN8A | Q9UQD0 | 14/20 | 0.46 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.46 |
| ▸ | SCN1A | P35498 | 11/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1682280 | 0.88 | HTR2A (0.48) | CHRM2CHRM3SCN8AOPRM1SCN1A | |
| SCHEMBL1682352 | 0.87 | HTR2A (0.48) | CHRM2CHRM3SCN8AOPRM1SCN1A | |
| SCHEMBL1682296 | 0.85 | HTR2A (0.53) | CHRM2CHRM3OPRM1 | |
| SCHEMBL1682268 | 0.85 | USP2 (0.55) | KDM4EGAA | |
| SCHEMBL1682282 | 0.82 | MEN1 (0.48) | CHRM2CHRM3OPRM1 | |
| SCHEMBL1682312 | 0.81 | HTT (0.54) | CHRM2CHRM3 | |
| SCHEMBL1682317 | 0.81 | CHRM4 (0.50) | CHRM2CHRM3OPRM1 | |
| SCHEMBL1682265 | 0.81 | BCHE (0.53) | — | |
| SCHEMBL1682262 | 0.80 | CXCR4 (0.51) | OPRM1 | |
| SCHEMBL1682260 | 0.80 | CXCR4 (0.48) | CHRM2CHRM3SCN8AOPRM1SCN1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011043519-A2 | SULFONAMIDE DERIVATIVES AS SEROTONIN RECEPTOR ANTAGONIST AND SEROTONIN REUPTAKE INHIBITOR | KOREA INSTITUTE OF SCIENCE AND TECHNOLOGY (KR) | 2011-04-14 | — | — | WO | claimed |
| WO-2011043519-A2 | SULFONAMIDE DERIVATIVES AS SEROTONIN RECEPTOR ANTAGONIST AND SEROTONIN REUPTAKE INHIBITOR | KOREA INSTITUTE OF SCIENCE AND TECHNOLOGY (KR) | 2011-04-14 | — | — | WO | disclosed |