⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1101334 | 0.67 | — | — | |
| SCHEMBL9715202 | 0.66 | — | — | |
| SCHEMBL9393349 | 0.66 | — | — | |
| SCHEMBL1017724 | 0.62 | — | — | |
| SCHEMBL19925753 | 0.60 | — | — | |
| SCHEMBL7559055 | 0.59 | — | — | |
| SCHEMBL10592165 | 0.59 | — | — | |
| SCHEMBL15941183 | 0.59 | — | — | |
| SCHEMBL2916248 | 0.57 | — | — | |
| SCHEMBL7845280 | 0.56 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3083620-A1 | TETRAHYDROPYRIDOPYRAZINES MODULATORS OF GPR6 | Takeda Pharmaceutical Company Limited (JP) | 2016-10-26 | — | — | EP | claimed |
| WO-2015095728-A1 | TETRAHYDROPYRIDOPYRAZINES MODULATORS OF GPR6 | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2015-06-25 | — | — | WO | claimed |