SCHEMBL1101334

SCHEMBL1101334

NC(=O)C1CC=CC=N1

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL746463 0.80
SCHEMBL15196096 0.78
SCHEMBL9334066 0.78
SCHEMBL7903258 0.74 KDM4E (0.33)
SCHEMBL22132885 0.70
SCHEMBL7845280 0.68
SCHEMBL4597259 0.67
SCHEMBL16826850 0.67
SCHEMBL3707105 0.65
SCHEMBL7265383 0.64

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 76 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0493782-A2 Novel dihydropyridine amides, process for their preparation and drugs containing them BAYER AG (DE) 1992-07-08 EP claimed
EP-0288758-B1 DIHYDROPYRIDINAMIDES, PROCESS FOR THEIR PREPARATION AND THEIR USE IN MEDICINES BAYER AG (DE) 1991-08-14 EP claimed
US-5015650-A Antiarrhythmic agents, renal insufficiency treatment with dihydropyridine derivatives BAYER AKTIENGESELLSCHAFT (DE) 1991-05-14 US claimed
EP-0362632-A2 Basic 4-aryl-DHP amides, process for their preparation and their pharmaceutical use BAYER AG (DE) 1990-04-11 EP claimed
CN-88101927-A Dihydropyridine amides, its preparation method and application pharmaceutically 1988-11-16 CN claimed
EP-0288758-A2 Dihydropyridinamides, process for their preparation and their use in medicines BAYER AG (DE) 1988-11-02 EP claimed
CN-122103091-A 4-Phenoxyquinoline compound containing dihydropyridine amide and dihydropyridazinamide and application thereof 2026-05-29 CN disclosed
CN-122103091-A 4-Phenoxyquinoline compound containing dihydropyridine amide and dihydropyridazinamide and application thereof 2026-05-29 CN disclosed
CN-112789346-B Negative hydrogen ion donors as additives to reduce low-rate pre-ignition events 雪佛龙奥伦耐有限责任公司 2024-07-12 CN disclosed
EP-3861089-A1 HYDRIDE DONORS AS AN ADDITIVE FOR REDUCING LOW SPEED PRE-IGNITION EVENTS Chevron Oronite Company LLC (US) 2021-08-11 EP disclosed
CN-112789346-A Negative hydrogen ion donors as additives to reduce low speed pre-ignition events 雪佛龙奥伦耐有限责任公司 2021-05-11 CN disclosed
US-20200109343-A1 HYDRIDE DONORS AS AN ADDITIVE FOR REDUCING LOW SPEED PRE-IGNITION EVENTS CHEVRON ORONITE COMPANY LLC 2020-04-09 US disclosed
WO-2020070672-A1 HYDRIDE DONORS AS AN ADDITIVE FOR REDUCING LOW SPEED PRE-IGNITION EVENTS CHEVRON ORONITE COMPANY LLC (US) 2020-04-09 WO disclosed
EP-0288758-A2 Dihydropyridinamides, process for their preparation and their use in medicines BAYER AG (DE) 1988-11-02 EP disclosed
EP-0288758-A2 Dihydropyridinamides, process for their preparation and their use in medicines BAYER AG (DE) 1988-11-02 EP disclosed
EP-0288758-A2 Dihydropyridinamides, process for their preparation and their use in medicines BAYER AG (DE) 1988-11-02 EP disclosed
US-4753936-A CARDIOVASCULAR DISORDERS BAYER AKTIENGESELLSCHAFT (DE) 1988-06-28 US disclosed
US-4727079-A Brain-specific dopaminergic activity involving dihydropyridine carboxamides, dihydroquinoline and isoquinoline carboxamides UNIVERSITY OF FLORIDA (US) 1988-02-23 US disclosed
EP-0185964-A2 Dihydropyridine-carboxylic acid amides, process for their preparation and their use in medicaments BAYER AG (DE) 1986-07-02 EP disclosed
US-4556414-A Herbicidal dihydropyridine amides RHONE-POULENC AGROCHIMIE (FR) 1985-12-03 US disclosed