Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GBA1 | P04062 | 9/20 | 0.34 |
| ▸ | GBA2 | Q9HCG7 | 11/20 | 0.32 |
| ▸ | GAA | P10253 | 2/20 | 0.32 |
| ▸ | MGAM | O43451 | 2/20 | 0.32 |
| ▸ | UGCG | Q16739 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15072484 | 0.69 | EPHX2 (0.47) | GBA1 | |
| SCHEMBL19519584 | 0.68 | GBA1 (0.33) | GBA1 | |
| SCHEMBL20624274 | 0.68 | GBA1 (0.33) | GBA1 | |
| SCHEMBL8350328 | 0.63 | PYGB (0.32) | — | |
| SCHEMBL25366499 | 0.63 | GAA (0.37) | GAA | |
| SCHEMBL5551957 | 0.63 | GAA (0.37) | GAA | |
| SCHEMBL22409570 | 0.63 | GAA (0.37) | GAA | |
| SCHEMBL19326781 | 0.63 | GAA (0.37) | GAA | |
| SCHEMBL9699515 | 0.63 | GAA (0.37) | GAA | |
| SCHEMBL19326770 | 0.63 | GAA (0.37) | GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3083658-A2 | METHODS AND ASSAYS RELATING TO CIRCULATING TUMOR CELLS | President and Fellows of Harvard College (US) | 2016-10-26 | — | — | EP | disclosed |
| WO-2015095604-A2 | METHODS AND ASSAYS RELATING TO CIRCULATING TUMOR CELLS | PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) | 2015-06-25 | — | — | WO | disclosed |