Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 4/20 | 0.55 |
| ▸ | MEN1 | O00255 | 3/20 | 0.55 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.55 |
| ▸ | HPGD | P15428 | 2/20 | 0.55 |
| ▸ | CES1 | P23141 | 2/20 | 0.55 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.55 |
| ▸ | MAPT | P10636 | 2/20 | 0.55 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.55 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.55 |
| ▸ | PTPN1 | P18031 | 3/20 | 0.48 |
| ▸ | ERCC5 | P28715 | 1/20 | 0.48 |
| ▸ | FEN1 | P39748 | 1/20 | 0.48 |
| ▸ | PLOD2 | O00469 | 5/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | PLOD3 | O60568 | 3/20 | 0.46 |
| ▸ | PLOD1 | Q02809 | 3/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.46 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL523476 | 0.81 | PLOD2 (0.69) | KMT2AMEN1CYP3A4HPGDCES1 | |
| SCHEMBL9565951 | 0.79 | PLOD2 (0.67) | KMT2AMEN1CYP3A4HPGDCES1 | |
| SCHEMBL30846025 | 0.79 | PLOD2 (0.67) | KMT2AMEN1CYP3A4HPGDCES1 | |
| SCHEMBL9654173 | 0.79 | PLOD2 (0.67) | KMT2AMEN1CYP3A4HPGDCES1 | |
| SCHEMBL9630807 | 0.79 | PLOD2 (0.67) | KMT2AMEN1CYP3A4HPGDCES1 | |
| SCHEMBL10613054 | 0.79 | PLOD2 (0.67) | KMT2AMEN1CYP3A4HPGDCES1 | |
| SCHEMBL14537550 | 0.78 | KMT2A (0.59) | KMT2AMEN1CYP3A4HPGDCES1 | |
| SCHEMBL1682774 | 0.78 | MEN1 (0.59) | KMT2AMEN1CYP3A4HPGDCES1 | |
| SCHEMBL8641213 | 0.78 | KMT2A (0.59) | KMT2AMEN1CYP3A4HPGDCES1 | |
| SCHEMBL8911789 | 0.77 | PLOD2 (0.46) | KMT2AMEN1HPGDCES1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9101635-B2 | Inhibitors of filovirus entry into host cells | MICROBIOTIX, INC. (US) | 2015-08-11 | — | — | US | disclosed |
| US-20120189614-A1 | INHIBITORS OF FILOVIRUS ENTRY INTO HOST CELLS | Crobiotix, Inc. (US) | 2012-07-26 | — | — | US | disclosed |
| EP-2451278-A2 | INHIBITORS OF FILOVIRUS ENTRY INTO HOST CELLS | Microbiotix, Inc. (US) | 2012-05-16 | — | — | EP | disclosed |
| WO-2011046646-A2 | INHIBITORS OF FILOVIRUS ENTRY INTO HOST CELLS | MICROBIOTIX, INC. (US) | 2011-04-21 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120189614-A1 | INHIBITORS OF FILOVIRUS ENTRY INTO HOST CELLS | BSG, SLCO1B3, SLCO2B1 | KMT2A 4787/4885MEN1 4472/4885CYP3A4 612/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.